rcellminer: rcellminer: Molecular Profiles, Drug Response, and Chemical Structures for the NCI-60 Cell Lines

The NCI-60 cancer cell line panel has been used over the course of several decades as an anti-cancer drug screen. This panel was developed as part of the Developmental Therapeutics Program (DTP, http://dtp.nci.nih.gov/) of the U.S. National Cancer Institute (NCI). Thousands of compounds have been tested on the NCI-60, which have been extensively characterized by many platforms for gene and protein expression, copy number, mutation, and others (Reinhold, et al., 2012). The purpose of the CellMiner project (http://discover.nci.nih.gov/ cellminer) has been to integrate data from multiple platforms used to analyze the NCI-60 and to provide a powerful suite of tools for exploration of NCI-60 data.

Package details

AuthorAugustin Luna, Vinodh Rajapakse, Fabricio Sousa
Bioconductor views CellBasedAssays Cheminformatics CopyNumberVariation GeneExpression Pharmacogenetics Pharmacogenomics Software SystemsBiology Visualization aCGH miRNA
MaintainerAugustin Luna <lunaa@cbio.mskcc.org>, Vinodh Rajapakse <vinodh.rajapakse@nih.gov>, Fathi Elloumi <fathi.elloumi@nih.gov>
LicenseLGPL-3 + file LICENSE
URL http://discover.nci.nih.gov/cellminer/
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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rcellminer documentation built on Nov. 26, 2020, 2:02 a.m.