Description Usage Arguments Details Value Author(s) References See Also Examples
The function combines several pvalue estimated from the same null hypothesis in different studies involving independent data.
1 2  combine.test(p, weight, method = c("fisher", "z.transform", "logit"),
hetero = FALSE, na.rm = FALSE)

p 
vector of pvalues 
weight 
vector of weights (e.g. sample size of each study) 
method 

hetero 

na.rm 

The pvalues must be onesided and computed from the same null hypothesis.
pvalue
Benjamin HaibeKains
Whitlock, M. C. (2005) "Combining probability from independent tests: the weighted Zmethod is superior to Fisher's approach", J. Evol. Biol., 18, pages 1368–1373.
1 2 3 4 5 6 7  p < c(0.01, 0.13, 0.07, 0.2)
w < c(100, 50, 200, 30)
#with equal weights
combine.test(p=p, method="z.transform")
#with pvalues weighted by the sample size of the studies
combine.test(p=p, weight=w, method="z.transform")

Loading required package: survival
Loading required package: prodlim
[1] 0.001956598
[1] 0.004182589
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