Description Usage Arguments Details Value Author(s) References See Also Examples
This function compares two D indices from their betas and standard errors as computed by a Cox model for instance. The statistical test is a Student t test for dependent samples. The two D indices must be computed using the D.index
function from the same survival data.
1 | dindex.comp(dindex1, dindex2)
|
dindex1 |
first D index |
dindex2 |
second D index |
The two D indices must be computed using the D.index
function from the same samples (and corresponding survival data). The function uses a Student t test for dependent samples.
p.value |
p-value from the Wilcoxon rank sum test for the comparison dindex1 > dindex2 |
dindex1 |
value of the first D index |
dindex2 |
value of the second D index |
Benjamin Haibe-Kains
Haibe-Kains, B. and Desmedt, C. and Sotiriou, C. and Bontempi, G. (2008) "A comparative study of survival models for breast cancer prognostication based on microarray data: does a single gene beat them all?", Bioinformatics, 24, 19, pages 2200–2208.
1 2 3 4 5 6 7 8 9 10 | set.seed(12345)
age <- rnorm(100, 50, 10)
size <- rexp(100,1)
stime <- rexp(100)
cens <- runif(100,.5,2)
sevent <- as.numeric(stime <= cens)
stime <- pmin(stime, cens)
d1 <- D.index(x=age, surv.time=stime, surv.event=sevent)
d2 <- D.index(x=size, surv.time=stime, surv.event=sevent)
dindex.comp(d1, d2)
|
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