Nothing
binomial.glm <- function(formula, data=NULL, trials, burnin, n.sample, thin=1, n.chains=1, n.cores=1, prior.mean.beta=NULL, prior.var.beta=NULL, MALA=TRUE, verbose=TRUE)
{
##############################################
#### Format the arguments and check for errors
##############################################
#### Verbose
a <- common.verbose(verbose)
#### Frame object
frame.results <- common.frame(formula, data, "binomial")
K <- frame.results$n
p <- frame.results$p
X <- frame.results$X
X.standardised <- frame.results$X.standardised
X.sd <- frame.results$X.sd
X.mean <- frame.results$X.mean
X.indicator <- frame.results$X.indicator
offset <- frame.results$offset
Y <- frame.results$Y
which.miss <- frame.results$which.miss
n.miss <- frame.results$n.miss
#### Check on MALA argument
if(length(MALA)!=1) stop("MALA is not length 1.", call.=FALSE)
if(!is.logical(MALA)) stop("MALA is not logical.", call.=FALSE)
#### Check and format the trials argument
if(sum(is.na(trials))>0) stop("the numbers of trials has missing 'NA' values.", call.=FALSE)
if(!is.numeric(trials)) stop("the numbers of trials has non-numeric values.", call.=FALSE)
int.check <- K-sum(ceiling(trials)==floor(trials))
if(int.check > 0) stop("the numbers of trials has non-integer values.", call.=FALSE)
if(min(trials)<=0) stop("the numbers of trials has zero or negative values.", call.=FALSE)
failures <- trials - Y
if(sum(Y>trials, na.rm=TRUE)>0) stop("the response variable has larger values that the numbers of trials.", call.=FALSE)
#### Priors
if(is.null(prior.mean.beta)) prior.mean.beta <- rep(0, p)
if(is.null(prior.var.beta)) prior.var.beta <- rep(100000, p)
common.prior.beta.check(prior.mean.beta, prior.var.beta, p)
#### Compute the blocking structure for beta
block.temp <- common.betablock(p)
beta.beg <- block.temp[[1]]
beta.fin <- block.temp[[2]]
n.beta.block <- block.temp[[3]]
list.block <- as.list(rep(NA, n.beta.block*2))
for(r in 1:n.beta.block)
{
list.block[[r]] <- beta.beg[r]:beta.fin[r]-1
list.block[[r+n.beta.block]] <- length(list.block[[r]])
}
#### MCMC quantities - burnin, n.sample, thin
common.burnin.nsample.thin.check(burnin, n.sample, thin)
########################
#### Run the MCMC chains
########################
if(n.chains==1)
{
#### Only 1 chain
results <- binomial.glmMCMC(Y=Y, failures=failures, trials=trials, offset=offset, X.standardised=X.standardised, K=K, p=p, which.miss=which.miss, n.miss=n.miss, burnin=burnin, n.sample=n.sample, thin=thin, MALA=MALA, n.beta.block=n.beta.block, list.block=list.block, prior.mean.beta=prior.mean.beta, prior.var.beta=prior.var.beta, verbose=verbose, chain=1)
}else if(n.chains > 1 & ceiling(n.chains)==floor(n.chains) & n.cores==1)
{
#### Multiple chains in series
results <- as.list(rep(NA, n.chains))
for(i in 1:n.chains)
{
results[[i]] <- binomial.glmMCMC(Y=Y, failures=failures, trials=trials, offset=offset, X.standardised=X.standardised, K=K, p=p, which.miss=which.miss, n.miss=n.miss, burnin=burnin, n.sample=n.sample, thin=thin, MALA=MALA, n.beta.block=n.beta.block, list.block=list.block, prior.mean.beta=prior.mean.beta, prior.var.beta=prior.var.beta, verbose=verbose, chain=i)
}
}else if(n.chains > 1 & ceiling(n.chains)==floor(n.chains) & n.cores>1 & ceiling(n.cores)==floor(n.cores))
{
#### Multiple chains in parallel
results <- as.list(rep(NA, n.chains))
if(verbose)
{
compclust <- makeCluster(n.cores, outfile="CARBayesprogress.txt")
cat("The current progress of the model fitting algorithm has been output to CARBayesprogress.txt in the working directory")
}else
{
compclust <- makeCluster(n.cores)
}
results <- clusterCall(compclust, fun=binomial.glmMCMC, Y=Y, failures=failures, trials=trials, offset=offset, X.standardised=X.standardised, K=K, p=p, which.miss=which.miss, n.miss=n.miss, burnin=burnin, n.sample=n.sample, thin=thin, MALA=MALA, n.beta.block=n.beta.block, list.block=list.block, prior.mean.beta=prior.mean.beta, prior.var.beta=prior.var.beta, verbose=verbose, chain="all")
stopCluster(compclust)
}else
{
stop("n.chains or n.cores are not positive integers.", call.=FALSE)
}
#### end timer
if(verbose)
{
cat("\nSummarising results.\n")
}else
{}
###################################
#### Summarise and save the results
###################################
if(n.chains==1)
{
## Compute the acceptance rates
accept.beta <- 100 * results$accept[1] / results$accept[2]
accept.final <- c(accept.beta)
names(accept.final) <- c("beta")
## Compute the model fit criterion
mean.beta <- apply(results$samples.beta, 2, mean)
mean.logit <- as.numeric(X.standardised %*% mean.beta) + offset
mean.prob <- exp(mean.logit) / (1 + exp(mean.logit))
fitted.mean <- trials * mean.prob
deviance.fitted <- -2 * sum(dbinom(x=Y, size=trials, prob=mean.prob, log=TRUE), na.rm=TRUE)
modelfit <- common.modelfit(results$samples.loglike, deviance.fitted)
## Create the Fitted values and residuals
fitted.values <- apply(results$samples.fitted, 2, mean)
response.residuals <- as.numeric(Y) - fitted.values
pearson.residuals <- response.residuals /sqrt(fitted.values * (1 - mean.prob))
residuals <- data.frame(response=response.residuals, pearson=pearson.residuals)
## Create MCMC objects and back transform the regression parameters
samples.beta.orig <- common.betatransform(results$samples.beta, X.indicator, X.mean, X.sd, p, FALSE)
samples <- list(beta=mcmc(samples.beta.orig), fitted=mcmc(results$samples.fitted), Y=mcmc(results$samples.Y))
#### Create a summary object
n.keep <- floor((n.sample - burnin)/thin)
summary.beta <- t(rbind(apply(samples$beta, 2, mean), apply(samples$beta, 2, quantile, c(0.025, 0.975))))
summary.beta <- cbind(summary.beta, rep(n.keep, p), rep(accept.beta,p), effectiveSize(samples.beta.orig), geweke.diag(samples.beta.orig)$z)
rownames(summary.beta) <- colnames(X)
colnames(summary.beta) <- c("Mean", "2.5%", "97.5%", "n.sample", "% accept", "n.effective", "Geweke.diag")
summary.results <- summary.beta
summary.results[ , 1:3] <- round(summary.results[ , 1:3], 4)
summary.results[ , 4:7] <- round(summary.results[ , 4:7], 1)
}else
{
## Compute the acceptance rates
accept.temp <- lapply(results, function(l) l[["accept"]])
accept.temp2 <- do.call(what=rbind, args=accept.temp)
accept.beta <- 100 * sum(accept.temp2[ ,1]) / sum(accept.temp2[ ,2])
accept.final <- c(accept.beta)
names(accept.final) <- c("beta")
## Extract the samples into separate lists
samples.beta.list <- lapply(results, function(l) l[["samples.beta"]])
samples.loglike.list <- lapply(results, function(l) l[["samples.loglike"]])
samples.fitted.list <- lapply(results, function(l) l[["samples.fitted"]])
samples.Y.list <- lapply(results, function(l) l[["samples.Y"]])
## Convert the samples into separate matrix objects
samples.beta.matrix <- do.call(what=rbind, args=samples.beta.list)
samples.loglike.matrix <- do.call(what=rbind, args=samples.loglike.list)
samples.fitted.matrix <- do.call(what=rbind, args=samples.fitted.list)
## Compute the model fit criteria
mean.beta <- apply(samples.beta.matrix, 2, mean)
mean.logit <- as.numeric(X.standardised %*% mean.beta) + offset
mean.prob <- exp(mean.logit) / (1 + exp(mean.logit))
fitted.mean <- trials * mean.prob
deviance.fitted <- -2 * sum(dbinom(x=Y, size=trials, prob=mean.prob, log=TRUE), na.rm=TRUE)
modelfit <- common.modelfit(samples.loglike.matrix, deviance.fitted)
## Create the Fitted values and residuals
fitted.values <- apply(samples.fitted.matrix, 2, mean)
response.residuals <- as.numeric(Y) - fitted.values
pearson.residuals <- response.residuals /sqrt(fitted.values * (1 - mean.prob))
residuals <- data.frame(response=response.residuals, pearson=pearson.residuals)
## Backtransform the regression parameters
samples.beta.list <- samples.beta.list
for(j in 1:n.chains)
{
samples.beta.list[[j]] <- common.betatransform(samples.beta.list[[j]], X.indicator, X.mean, X.sd, p, FALSE)
}
samples.beta.matrix <- do.call(what=rbind, args=samples.beta.list)
## Create MCMC objects
beta.temp <- samples.beta.list
loglike.temp <- samples.loglike.list
fitted.temp <- samples.fitted.list
Y.temp <- samples.Y.list
for(j in 1:n.chains)
{
beta.temp[[j]] <- mcmc(samples.beta.list[[j]])
loglike.temp[[j]] <- mcmc(samples.loglike.list[[j]])
fitted.temp[[j]] <- mcmc(samples.fitted.list[[j]])
Y.temp[[j]] <- mcmc(samples.Y.list[[j]])
}
beta.mcmc <- as.mcmc.list(beta.temp)
fitted.mcmc <- as.mcmc.list(fitted.temp)
Y.mcmc <- as.mcmc.list(Y.temp)
samples <- list(beta=beta.mcmc, fitted=fitted.mcmc, Y=Y.mcmc)
## Create a summary object
n.keep <- floor((n.sample - burnin)/thin)
summary.beta <- t(rbind(apply(samples.beta.matrix, 2, mean), apply(samples.beta.matrix, 2, quantile, c(0.025, 0.975))))
summary.beta <- cbind(summary.beta, rep(n.keep, p), rep(accept.beta,p), effectiveSize(beta.mcmc), gelman.diag(beta.mcmc)$psrf[ ,2])
rownames(summary.beta) <- colnames(X)
colnames(summary.beta) <- c("Mean", "2.5%", "97.5%", "n.sample", "% accept", "n.effective", "PSRF (upper 95% CI)")
summary.results <- summary.beta
summary.results[ , 1:3] <- round(summary.results[ , 1:3], 4)
summary.results[ , 4:7] <- round(summary.results[ , 4:7], 1)
}
###################################
#### Compile and return the results
###################################
model.string <- c("Likelihood model - Binomial (logit link function)", "\nRandom effects model - None\n")
n.total <- floor((n.sample - burnin) / thin) * n.chains
mcmc.info <- c(n.total, n.sample, burnin, thin, n.chains)
names(mcmc.info) <- c("Total samples", "n.sample", "burnin", "thin", "n.chains")
results <- list(summary.results=summary.results, samples=samples, fitted.values=fitted.values, residuals=residuals, modelfit=modelfit, accept=accept.final, localised.structure=NULL, formula=formula, model=model.string, mcmc.info=mcmc.info, X=X)
class(results) <- "CARBayes"
if(verbose)
{
b<-proc.time()
cat("Finished in ", round(b[3]-a[3], 1), "seconds.\n")
}else
{}
return(results)
}
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