diff_gen_PPI: Generate the scaled node score and scaled edge score for...

Description Usage Arguments Value Author(s) Examples

View source: R/diff_gen_PPI.R

Description

Compute the F-statistic and ECF-statistic and then standardize them

Usage

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diff_gen_PPI(data1, data2, PPI)

Arguments

data1

The first gene expression dataset(with rows corresponding to samples)

data2

The second gene expression dataset

PPI

A matrix with two columns containing the protein interaction pairs

Value

A list containing:

scaled_node_score

The standardized F-statistic measuring the differential expression of each gene

scaled_edge_score

The standardized ECF-statistic measuring the differential correlation of each gene pair

Author(s)

Haisu Ma

Examples

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data(simulated_data)
data(PPI)
data1 <- simulated_data[[1]]
data2 <- simulated_data[[7]]
colnames(data1)<-colnames(data2)<-as.character(1:500)
test <- diff_gen_PPI(data1[,1:20],data2[,1:20],PPI)

COSINE documentation built on May 1, 2019, 10:21 p.m.