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Many inherited biases and effects exists in RNA-seq due to both biological and technical effects. We observed the biological variance of testing target transcripts can influence the yield of sequencing reads, which might indicate a resource competition existing in RNA-seq. We developed this package to capture the bias depending on local sequence and perform the correction of this type of bias by borrowing information from spike-in measurement.
Package details |
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Author | Guoshuai Cai |
Maintainer | Guoshuai Cai <GCAI.bioinfo@gmail.com> |
License | GPL (>= 2) |
Version | 1.0 |
Package repository | View on CRAN |
Installation |
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