Many inherited biases and effects exists in RNA-seq due to both biological and technical effects. We observed the biological variance of testing target transcripts can influence the yield of sequencing reads, which might indicate a resource competition existing in RNA-seq. We developed this package to capture the bias depending on local sequence and perform the correction of this type of bias by borrowing information from spike-in measurement.
|Date of publication||2014-07-16 01:07:26|
|Maintainer||Guoshuai Cai <[email protected]>|
|License||GPL (>= 2)|
|Package repository||View on CRAN|
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