calculate_auc: Calculate Area Under the Curve

In HaDeX2: Analysis and Visualisation of Hydrogen/Deuterium Exchange Mass Spectrometry Data

Calculate Area Under the Curve

Description

Calculates area under the deuterium uptake curve

Usage

calculate_auc(
  uptake_dat,
  protein = uptake_dat[["Protein"]][1],
  state = uptake_dat[["State"]][1],
  preserve_values = FALSE
)

Arguments

uptake_dat	data with deuterium uptake values, calculated e.q. by create_uptake_dataset
protein	chosen protein
state	state included in calculations
preserve_values	indicator if the original columns form uptake_dat should be preserve in the result

Details

The AUC is calculated on the data normalized to unit square by division by maximum values of exposure time and deuterium uptake, respectively.

Value

a data.frame object

See Also

read_hdx create_uptake_dataset

Examples

uptake_dat <- create_uptake_dataset(alpha_dat)
head(calculate_auc(uptake_dat))

HaDeX2 documentation built on Feb. 9, 2026, 5:07 p.m.