ISOpure.calculate.tac: Perform calculation for Tumour Adjacent Cell (TAC) profiles

Description Usage Arguments Value Author(s)

View source: R/ISOpure.calculate.tac.R

Description

Performs the mathematical calculations taking bulk tumor data and deconvolved profiles and returning deconvolved tumour adjacent cell profiles.

Usage

1
ISOpure.calculate.tac(tumor.profiles, deconvolved.profiles, purity.estimates)

Arguments

tumor.profiles

a GxD matrix representing gene expression profiles of heterogeneous (mixed) tumor samples, where G is the number of genes, D is the number of tumor samples.

deconvolved.profiles

a GxD matrix representing gene expression profiles of purified (ISOpure output) tumor samples, where G is the number of genes, D is the number of tumor samples.

purity.estimates

a vector D representing the purity estimates (output from ISOpure)

Value

a GxD matrix representing gene expression profiles of purified (ISOpure output) tumor adjacent cell signal, where G is the number of genes, D is the number of tumor samples.

Author(s)

Natalie Fox


ISOpureR documentation built on May 2, 2018, 1:04 a.m.