ISOpure.calculate.tac: Perform calculation for Tumour Adjacent Cell (TAC) profiles
In ISOpureR: Deconvolution of Tumour Profiles
Description
Usage
Arguments
Value
Author(s)
Description
Performs the mathematical calculations taking bulk tumor data and deconvolved profiles
and returning deconvolved tumour adjacent cell profiles.
Usage
1
ISOpure.calculate.tac(tumor.profiles, deconvolved.profiles, purity.estimates)
Arguments
tumor.profiles
a GxD matrix representing gene expression profiles of heterogeneous (mixed)
tumor samples, where G is the number of genes, D is the number of tumor samples.
deconvolved.profiles
a GxD matrix representing gene expression profiles of purified (ISOpure output)
tumor samples, where G is the number of genes, D is the number of tumor samples.
purity.estimates
a vector D representing the purity estimates (output from ISOpure)
Value
a GxD matrix representing gene expression profiles of purified (ISOpure output)
tumor adjacent cell signal, where G is the number of genes, D is the number of tumor samples.
Author(s)
Natalie Fox
ISOpureR documentation built on May 11, 2019, 1:02 a.m.
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Description Usage Arguments Value Author(s)
Description
Performs the mathematical calculations taking bulk tumor data and deconvolved profiles and returning deconvolved tumour adjacent cell profiles.
Usage
1 | ISOpure.calculate.tac(tumor.profiles, deconvolved.profiles, purity.estimates)
|
Arguments
tumor.profiles |
a GxD matrix representing gene expression profiles of heterogeneous (mixed) tumor samples, where G is the number of genes, D is the number of tumor samples. |
deconvolved.profiles |
a GxD matrix representing gene expression profiles of purified (ISOpure output) tumor samples, where G is the number of genes, D is the number of tumor samples. |
purity.estimates |
a vector D representing the purity estimates (output from ISOpure) |
Value
a GxD matrix representing gene expression profiles of purified (ISOpure output) tumor adjacent cell signal, where G is the number of genes, D is the number of tumor samples.
Author(s)
Natalie Fox
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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