ISOpureS1.model_optimize.omega.omega_deriv_loglikelihood: Compute the derivative of loglikelihood relevant to omega for...
In ISOpureR: Deconvolution of Tumour Profiles
Description
Usage
Arguments
Value
Author(s)
Description
Compute the derivative of the part of the loglikelihood function relevant to omega
with respect to (log) omega, in step 1. Instead of performing constrained optimization on omega
directly, we optimize the log of omega in an unconstrained fashion.
Usage
1
ISOpureS1.model_optimize.omega.omega_deriv_loglikelihood(ww, tumordata, model)
Arguments
ww
(K-1)x1 matrix, log(omega), where the entries in omega are constrained to add to 1
where K-1 is the number of normal samples
tumordata
a GxD matrix representing gene expression profiles of tumor samples
model
list containing all the parameters to be optimized
Value
The negative derivative of the part of the loglikelihood function relevant to omega
with respect to (log) omega
Author(s)
Gerald Quon, Catalina Anghel, Francis Nguyen
ISOpureR documentation built on May 11, 2019, 1:02 a.m.
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Description Usage Arguments Value Author(s)
Description
Compute the derivative of the part of the loglikelihood function relevant to omega with respect to (log) omega, in step 1. Instead of performing constrained optimization on omega directly, we optimize the log of omega in an unconstrained fashion.
Usage
1 | ISOpureS1.model_optimize.omega.omega_deriv_loglikelihood(ww, tumordata, model)
|
Arguments
ww |
(K-1)x1 matrix, log(omega), where the entries in omega are constrained to add to 1 where K-1 is the number of normal samples |
tumordata |
a GxD matrix representing gene expression profiles of tumor samples |
model |
list containing all the parameters to be optimized |
Value
The negative derivative of the part of the loglikelihood function relevant to omega with respect to (log) omega
Author(s)
Gerald Quon, Catalina Anghel, Francis Nguyen
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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