Description Usage Arguments Details Value References Examples
Prepare dose-effect data for evaluation.
1 | dataprep(dose, ntot, nfx)
|
dose |
A numeric vector of unique, chemical concentrations (see Details). |
ntot |
A numeric vector of the number of individuals that were tested at each dose. |
nfx |
A numeric vector of the number of individuals that were affected at each dose. |
The input data are expected to be summarized by dose. If duplicate doses are provided, an error will be thrown.
A data frame with eight columns (ordered by dose and proportion affected), seven numeric vectors and one logical vector:
dose
= chemical concentrations.
ntot
= the number of individuals that were tested at each
dose.
nfx
= the number of individuals that were affected at each
dose.
rec
= the record number corresponding to the input vectors
dose
, ntot
, nfx
.
pfx
= the proportion of individuals that were affected at
each dose.
log10dose
= log transformed dose, log10(dose)
.
bitpfx
= probit transformed proportional affected,
probit(pfx)
.
fxcateg
= effects category: 0 for none affected, 100 for all
affected, and 50 for other proportions affected.
LWkeep
= logical vector identifying records to keep for
Litchfield and Wilcoxon (1949, step A1) method.
Litchfield, JT Jr. and F Wilcoxon. 1949. A simplified method of evaluating dose-effect experiments. Journal of Pharmacology and Experimental Therapeutics 96(2):99-113. [link].
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