sgRNA: sgRNA dataset

In NBBttest: Negative Binomial Beta t-Test

sgRNA dataset

Description

This dataset was created by simulating single guide RNAs to edit genes.

Usage

data("sgRNA")

Format

A data frame with 1000 observations on the following 11 variables.

gene

a factor with levels

sgRNA

a factor with levels

class

a factor with levels

L1

a numeric vector

L2

a numeric vector

L3

a numeric vector

L4

a numeric vector

H1

a numeric vector

H2

a numeric vector

H3

a numeric vector

H4

a numeric vector

Details

The dataset is CRISPR screening data. Each gene was edited by 10 sgRNAs that contains a targeting sequence (crRNA sequence) and a Cas9 nuclease-recruiting sequence (tracrRNA). L1-L4 samples were lowly targeted by sgRNAs and H1-H4 were highly targeted by sgRNAs.

Examples

data(sgRNA)

NBBttest documentation built on May 30, 2022, 1:05 a.m.