Files in PopED
Population (and Individual) Optimal Experimental Design

inst
inst/examples
inst/examples/ex.1.b.PK.1.comp.oral.md.re-parameterize.R
inst/examples/two_comp_oral_CL.c
inst/examples/ex.9.PK.2.comp.oral.md.ode.compiled.R inst/examples/ex.10.PKPD.HCV.compiled.R inst/examples/ex.7.PK.1.comp.maturation.R inst/examples/ex.1.c.PK.1.comp.oral.md.ODE.compiled.R inst/examples/ex.1.a.PK.1.comp.oral.md.intro.R inst/examples/ex.8.tmdd_qss_one_target_compiled.R inst/examples/ex.2.a.warfarin.evaluate.R inst/examples/ex.3.b.PKPD.1.comp.oral.md.imax.ED-opt.R inst/examples/ex.4.PKPD.1.comp.emax.R inst/examples/ex.2.e.warfarin.Ds.R inst/examples/ex.2.b.warfarin.optimize.R inst/examples/ex.6.PK.1.comp.oral.sd.R inst/examples/ex.2.c.warfarin.ODE.compiled.R inst/examples/ex.5.PD.emax.hill.R inst/examples/ex.2.d.warfarin.ED.R
inst/examples/tmdd_qss_one_target.c
inst/examples/one_comp_oral_CL.c
inst/examples/HCV_ode.c
inst/examples/ex.3.a.PKPD.1.comp.oral.md.imax.D-opt.R
inst/CITATION
inst/doc
inst/doc/intro-poped.html
inst/doc/intro-poped.Rmd inst/doc/intro-poped.R
inst/shinyapp
inst/shinyapp/ui.R inst/shinyapp/server.R
inst/shinyapp/www
inst/shinyapp/www/poped_splash.png
tests
tests/testthat.R
tests/testthat
tests/testthat/PopED_output_summary_mfea_opt_1.txt
tests/testthat/PopED_output_summary_D_cont_opt_1.txt
tests/testthat/examples_fcn_doc
tests/testthat/examples_fcn_doc/examples_mftot.R tests/testthat/examples_fcn_doc/examples_RS_opt_gen.R tests/testthat/examples_fcn_doc/examples_ed_mftot.R tests/testthat/examples_fcn_doc/warfarin_ed.R tests/testthat/examples_fcn_doc/examples_rand.R tests/testthat/examples_fcn_doc/examples_feps.add.R tests/testthat/examples_fcn_doc/examples_ff.PK.1.comp.oral.sd.CL.R tests/testthat/examples_fcn_doc/examples_LEDoptim.R tests/testthat/examples_fcn_doc/examples_blockfinal.R tests/testthat/examples_fcn_doc/examples_RS_opt.R tests/testthat/examples_fcn_doc/examples_zeros.R tests/testthat/examples_fcn_doc/examples_ff.PKPD.1.comp.oral.md.CL.imax.R tests/testthat/examples_fcn_doc/examples_mftot0.R tests/testthat/examples_fcn_doc/examples_a_line_search.R tests/testthat/examples_fcn_doc/examples_optim_ARS.R tests/testthat/examples_fcn_doc/examples_test_mat_size.R tests/testthat/examples_fcn_doc/examples_mf6.R tests/testthat/examples_fcn_doc/examples_Dtrace.R tests/testthat/examples_fcn_doc/examples_Doptim.R tests/testthat/examples_fcn_doc/examples_ed_laplace_ofv.R tests/testthat/examples_fcn_doc/examples_fileparts.R tests/testthat/examples_fcn_doc/examples_test_for_zeros.R tests/testthat/examples_fcn_doc/examples_isfield.R tests/testthat/examples_fcn_doc/examples_ff.PK.1.comp.oral.md.KE.R tests/testthat/examples_fcn_doc/examples_ones.R tests/testthat/examples_fcn_doc/examples_mftot4.R tests/testthat/examples_fcn_doc/examples_calc_ofv_and_fim.R tests/testthat/examples_fcn_doc/examples_feval.R tests/testthat/examples_fcn_doc/examples_getTruncatedNormal.R tests/testthat/examples_fcn_doc/examples_mf5.R tests/testthat/examples_fcn_doc/examples_model_prediction.R tests/testthat/examples_fcn_doc/examples_ff.PK.1.comp.oral.sd.KE.R tests/testthat/examples_fcn_doc/examples_diag_matlab.R tests/testthat/examples_fcn_doc/examples_poped-package.R tests/testthat/examples_fcn_doc/examples_ff.PK.1.comp.oral.md.CL.R tests/testthat/examples_fcn_doc/examples_poped.choose.R tests/testthat/examples_fcn_doc/examples_pargen.R tests/testthat/examples_fcn_doc/examples_mftot6.R tests/testthat/examples_fcn_doc/examples_mf7.R tests/testthat/examples_fcn_doc/examples_mftot1.R tests/testthat/examples_fcn_doc/examples_mfea.R tests/testthat/examples_fcn_doc/examples_LinMatrixL.R tests/testthat/examples_fcn_doc/examples_isempty.R tests/testthat/examples_fcn_doc/examples_gradf_eps.R tests/testthat/examples_fcn_doc/examples_getfulld.R tests/testthat/examples_fcn_doc/examples_create.poped.database.R tests/testthat/examples_fcn_doc/examples_blockopt.R tests/testthat/examples_fcn_doc/examples_optim_LS.R tests/testthat/examples_fcn_doc/examples_build_sfg.R tests/testthat/examples_fcn_doc/examples_toc.R tests/testthat/examples_fcn_doc/examples_mftot7.R tests/testthat/examples_fcn_doc/examples_bfgsb_min.R tests/testthat/examples_fcn_doc/examples_calc_autofocus.R tests/testthat/examples_fcn_doc/examples_LinMatrixH.R tests/testthat/examples_fcn_doc/examples_randperm.R tests/testthat/examples_fcn_doc/examples_ff.PKPD.1.comp.sd.CL.emax.R tests/testthat/examples_fcn_doc/examples_tic.R tests/testthat/examples_fcn_doc/warfarin_optimize.R tests/testthat/examples_fcn_doc/examples_mftot5.R tests/testthat/examples_fcn_doc/examples_summary.poped_optim.R tests/testthat/examples_fcn_doc/examples_mf.R tests/testthat/examples_fcn_doc/examples_blockexp.R tests/testthat/examples_fcn_doc/examples_mf3.R tests/testthat/examples_fcn_doc/examples_calc_ofv_and_grad.R tests/testthat/examples_fcn_doc/examples_create_design_space.R tests/testthat/examples_fcn_doc/examples_evaluate.fim.R tests/testthat/examples_fcn_doc/examples_LinMatrixLH.R tests/testthat/examples_fcn_doc/examples_randn.R tests/testthat/examples_fcn_doc/examples_blockheader.R tests/testthat/examples_fcn_doc/examples_mf8.R tests/testthat/examples_fcn_doc/examples_plot_efficiency_of_windows.R tests/testthat/examples_fcn_doc/examples_ofv_criterion.R tests/testthat/examples_fcn_doc/examples_poped_optim.R tests/testthat/examples_fcn_doc/examples_poped_optimize.R tests/testthat/examples_fcn_doc/examples_size.R tests/testthat/examples_fcn_doc/examples_downsizing_general_design.R tests/testthat/examples_fcn_doc/examples_test_for_max.R tests/testthat/examples_fcn_doc/examples_evaluate.e.ofv.fim.R tests/testthat/examples_fcn_doc/examples_LinMatrixL_occ.R tests/testthat/examples_fcn_doc/examples_ofv_fim.R tests/testthat/examples_fcn_doc/warfarin_basic.R tests/testthat/examples_fcn_doc/examples_create_design.R tests/testthat/examples_fcn_doc/examples_evaluate_design.R tests/testthat/examples_fcn_doc/examples_test_for_min.R tests/testthat/examples_fcn_doc/examples_cell.R tests/testthat/examples_fcn_doc/examples_log_prior_pdf.R tests/testthat/examples_fcn_doc/examples_plot_model_prediction.R tests/testthat/examples_fcn_doc/examples_get_all_params.R
tests/testthat/PopED_output_summary_ED_Laplace_opt.txt
tests/testthat/PopED_output_summary_RS.txt
tests/testthat/test_evaluate.fim.R tests/testthat/test_optimization.R tests/testthat/helper_options.R tests/testthat/test_E_family.R
tests/testthat/PopED_output_summary_RS_1.txt
tests/testthat/helper_functions.R tests/testthat/test_create_databases.R tests/testthat/test_examples.R tests/testthat/test_distributions.R tests/testthat/test_evaluate_design.R tests/testthat/test_predictions.R
NAMESPACE
NEWS
R
R/mf3.R R/mftot1.R R/zeros.R R/m4.R R/mftot5.R R/summary.poped_optim.R R/mfea.R R/mftot7.R R/models.R R/blockopt.R R/getfulld.R R/v.R R/write_matrix.R R/write_iterationfile.R R/line_search_uc.R R/ed_mftot.R R/datestr_poped.R R/mf7.R R/gradofv_xt.R R/trace_matrix.R R/ones.R R/mf_all.R R/test_for_max.R R/dfimdalpha.R R/fileparts.R R/projected_gradient_norm.R R/size.R R/mftot2.R R/feval.R R/ofv_criterion.R R/LEDoptim.R R/graddetmfxt.R R/bfgsb_min.R R/update_offdiag.R R/graddetmfxt_ext.R R/gradff.R R/gradfg.R R/kron_tmp.R R/a_line_search.R R/evaluate.e.ofv.fim.R R/mc_mean.R R/isnan.R R/mf5.R R/d2fimdalpha2.R R/matrix_any.R R/update_designinlist.R R/get_unfixed_params.R R/fullfile.R R/get_all_params.R R/start_parallel.R R/create_design.R R/hessian_eta_complex.R R/calc_ofv_and_fim.R R/RS_opt.R R/inv.R R/isempty.R R/evaluate_design.R R/get_cov_matrix_index.R R/poped_optimize.R R/line_search.R R/subspace_min.R R/test_mat_size.R R/mftot.R R/create.poped.database.R R/RS_opt_gen.R R/LinMatrixLH.R R/Dtrace.R R/ind_likelihood.R R/LinMatrixL.R R/mf8.R R/grouped_rand.R R/m3.R R/blockoptwrt.R R/graddetmfa_ext.R R/gradlndetmfxt_ext.R R/tic.R R/test_for_zeros.R R/convert_variables.R R/gradofv_a.R R/mftot4.R R/graddetmfa.R R/find_matlab.R R/poped_optim.R R/cell.R R/m2.R R/mftot0.R R/isinf.R R/ed_laplace_ofv.R R/model_prediction.R R/create_design_space.R R/isfield.R R/randn.R R/LinMatrixL_occ.R R/poped_gui.R R/matrix_all.R R/get_discrete_x.R R/fprintf.R R/toc.R R/pargen.R R/test_for_min.R R/Doptim.R R/linspace.R R/mftot6.R R/rem.R R/writet.R R/limit_value.R R/optim_LS.R R/median_hilow_poped.R R/rand.R R/PopED.R R/blockfinal.R R/get_vector_str.R R/gradfg_occ.R R/cauchy_point.R R/blockheader.R R/ofv_fim.R R/mf6.R R/get_fim_size.R R/numel.R R/getTruncatedNormal.R R/build_sfg.R R/plot_efficiency_of_windows.R R/mftot3.R R/blockexp.R R/grouped_rand_a.R R/log_prior_pdf.R R/evaluate.fim.R R/blockother.R R/randperm.R R/reshape_matlab.R R/gradtrmfxt.R R/hesskalpha2.R R/gradtrmfa.R R/mf.R R/gradlndetmfa_ext.R R/plot_model_prediction.R R/get_cv.R R/zzz.R R/downsizing_general_design.R R/diag_matlab.R R/find.largest.index.R R/LinMatrixH.R R/gradlndetmfxt.R R/optim_ARS.R R/m1.R R/gradlndetmfa.R R/ind_estimates.R
vignettes
vignettes/intro-poped_cache
vignettes/intro-poped_cache/html
vignettes/intro-poped_cache/html/cost_optimization_f0f2d6281f61cf558abf1fc1f5bdf3c8.rdx
vignettes/intro-poped_cache/html/optimize_a2c5cd3f5dcf8a020a7e81c8d4ea906a.RData
vignettes/intro-poped_cache/html/__packages
vignettes/intro-poped_cache/html/optimize_a2c5cd3f5dcf8a020a7e81c8d4ea906a.rdx
vignettes/intro-poped_cache/html/optimize_dose_cc36fad2848e2f8b1aad976956b56449.rdx
vignettes/intro-poped_cache/html/cost_optimization_f0f2d6281f61cf558abf1fc1f5bdf3c8.RData
vignettes/intro-poped_cache/html/optimize_dose_cc36fad2848e2f8b1aad976956b56449.rdb
vignettes/intro-poped_cache/html/optimize_a2c5cd3f5dcf8a020a7e81c8d4ea906a.rdb
vignettes/intro-poped_cache/html/unnamed-chunk-10_e364407314b7746b9082627be42c8a28.rdb
vignettes/intro-poped_cache/html/optimize_dose_cc36fad2848e2f8b1aad976956b56449.RData
vignettes/intro-poped_cache/html/unnamed-chunk-10_e364407314b7746b9082627be42c8a28.RData
vignettes/intro-poped_cache/html/cost_optimization_f0f2d6281f61cf558abf1fc1f5bdf3c8.rdb
vignettes/intro-poped_cache/html/unnamed-chunk-10_e364407314b7746b9082627be42c8a28.rdx
vignettes/intro-poped.Rmd
vignettes/intro-poped_files
vignettes/intro-poped_files/figure-html
vignettes/intro-poped_files/figure-html/simulate_with_BSV-1.png
vignettes/intro-poped_files/figure-html/unnamed-chunk-14-1.png
vignettes/intro-poped_files/figure-html/unnamed-chunk-12-1.png
vignettes/intro-poped_files/figure-html/unnamed-chunk-9-1.png
vignettes/intro-poped_files/figure-html/unnamed-chunk-10-1.png
vignettes/intro-poped_files/figure-html/unnamed-chunk-6-1.png
README.md
MD5
build
build/vignette.rds
DESCRIPTION
man
man/Dtrace.Rd man/isempty.Rd man/calc_ofv_and_fim.Rd man/create_design.Rd man/mftot3.Rd man/mftot5.Rd man/mf8.Rd man/downsizing_general_design.Rd man/mftot2.Rd man/calc_autofocus.Rd man/create_design_space.Rd man/calc_ofv_and_grad.Rd man/LinMatrixH.Rd man/ff.PK.1.comp.oral.md.KE.Rd man/LinMatrixLH.Rd man/test_for_max.Rd man/toc.Rd man/poped_gui.Rd man/mftot.Rd man/mftot1.Rd man/ff.PKPD.1.comp.sd.CL.emax.Rd man/convert_variables.Rd man/ones.Rd man/mf.Rd man/test_for_zeros.Rd man/plot_model_prediction.Rd man/fileparts.Rd man/zeros.Rd man/optim_LS.Rd man/rand.Rd man/mftot0.Rd man/feps.add.prop.Rd man/blockheader.Rd man/LinMatrixL.Rd man/getfulld.Rd man/mf3.Rd man/ff.PK.1.comp.oral.sd.KE.Rd man/blockexp.Rd man/Doptim.Rd man/poped_optimize.Rd man/median_hilow_poped.Rd man/model_prediction.Rd man/LEDoptim.Rd man/pargen.Rd man/LinMatrixL_occ.Rd man/test_for_min.Rd man/tic.Rd man/create.poped.database.Rd man/summary.poped_optim.Rd man/ff.PK.1.comp.oral.md.CL.Rd man/a_line_search.Rd man/getTruncatedNormal.Rd man/mfea.Rd man/ed_laplace_ofv.Rd man/test_mat_size.Rd man/mftot7.Rd man/evaluate_design.Rd man/blockopt.Rd man/randn.Rd man/evaluate.e.ofv.fim.Rd man/feps.add.Rd man/get_all_params.Rd man/plot_efficiency_of_windows.Rd man/mftot6.Rd man/ff.PKPD.1.comp.oral.md.CL.imax.Rd man/size.Rd man/feval.Rd man/mf6.Rd man/isfield.Rd man/mc_mean.Rd man/RS_opt.Rd man/ff.PK.1.comp.oral.sd.CL.Rd man/mftot4.Rd man/gradf_eps.Rd man/optim_ARS.Rd man/cell.Rd man/poped.choose.Rd man/inv.Rd man/efficiency.Rd man/ofv_criterion.Rd man/start_parallel.Rd man/get_rse.Rd man/mf5.Rd man/evaluate.fim.Rd man/poped_optim.Rd man/log_prior_pdf.Rd man/ed_mftot.Rd man/bfgsb_min.Rd man/RS_opt_gen.Rd man/get_unfixed_params.Rd man/blockfinal.Rd man/feps.prop.Rd man/PopED.Rd man/randperm.Rd man/diag_matlab.Rd man/mf7.Rd man/ofv_fim.Rd
PopED documentation built on May 29, 2017, 10:55 a.m.