# case1102: The Blood-Brain Barrier In Sleuth2: Data Sets from Ramsey and Schafer's "Statistical Sleuth (2nd Ed)"

## Description

The human brain is protected from bacteria and toxins, which course through the blood–stream, by a single layer of cells called the blood–brain barrier. These data come from an experiment (on rats, which process a similar barrier) to study a method of disrupting the barrier by infusing a solution of concentrated sugars.

## Usage

 `1` ```case1102 ```

## Format

A data frame with 34 observations on the following 9 variables.

`Brain`

Brain tumor count (per gm)

`Liver`

Liver count (per gm)

`Time`

Sacrifice time (in hours)

`Treat`

`Days`

Days post inoculation

`Sex`

Sex of the rat

`Weight`

Initial weight (in grams)

`Loss`

Weight loss (in grams)

`Tumor`

Tumor weight (in 10^(-4) grams)

## Source

Ramsey, F.L. and Schafer, D.W. (2002). The Statistical Sleuth: A Course in Methods of Data Analysis (2nd ed), Duxbury.

## Examples

 ```1 2 3 4``` ```str(case1102) plot(Brain/Liver ~ Time, case1102, log="xy", pch=ifelse(Treat=="BD", 19,21)) legend(10,0.1, pch=c(19,21), c("Saline control", "Barrier disruption")) ```

### Example output

```'data.frame':	34 obs. of  9 variables:
\$ Brain : num  41081 44286 102926 25927 42643 ...
\$ Liver : num  1456164 1602171 1601936 1776411 1351184 ...
\$ Time  : num  0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 3 ...
\$ Treat : Factor w/ 2 levels "BD","NS": 1 1 1 1 1 2 2 2 2 1 ...
\$ Days  : num  10 10 10 10 10 10 10 10 10 10 ...
\$ Sex   : Factor w/ 2 levels "F","M": 1 1 1 1 1 1 1 1 1 1 ...
\$ Weight: num  239 225 224 184 250 196 200 273 216 267 ...
\$ Loss  : num  5.9 4 -4.9 9.8 6 7.7 0.5 4 2.8 2.6 ...
\$ Tumor : num  221 246 61 168 164 260 27 308 93 73 ...
```

Sleuth2 documentation built on May 2, 2019, 7:01 a.m.