ast_alt_ratio_interpret: De Ritis Ratio (Ast/Alt Ratio)

In cliot: Clinical Indices and Outcomes Tools

De Ritis Ratio (Ast/Alt Ratio)

Description

The De Ritis Ratio has been used clinically and in research for almost 50 years and is simply the ratio of aspartate transferase to alanine transferase. Validated in many cohorts, interpretations vary, and as such, I simply define a ratio of above 0.8 as indicative of liver injury, commonly agreed upon in the literature.

Usage

ast_alt_ratio_interpret(ast, alt)

Arguments

ast	Numeric value of aspartate transferase (U/L).
alt	Numeric value of alanine transferase (U/L).

Value

A numeric value/vector with whether by De Ritis ratio, there is liver injury.

References

Botros M, Sikaris KA. The de ritis ratio: the test of time. Clin Biochem Rev. 2013 Nov;34(3):117-30. PMID: 24353357; PMCID: PMC3866949.

Examples

# The function is defined as
ast_alt_ratio_interpret(30, 25)

cliot documentation built on May 29, 2024, 11:13 a.m.