atria_bleeding_risk: ATRIA Bleeding Risk Score

In cliot: Clinical Indices and Outcomes Tools

ATRIA Bleeding Risk Score

Description

Calculates the ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Bleeding Risk Score. This tool stratifies the risk of major hemorrhage in patients with atrial fibrillation who are taking warfarin. It outperforms the HAS-BLED score in predicting major bleeding events.

Usage

atria_bleeding_risk(age, sex, hemoglobin_g_dl, egfr_ml_min, prior_bleeding, hypertension)

Arguments

age	Numeric. Patient age in years. (>= 75 years adds +2 points).
sex	String. Patient sex ("Male" or "Female"). Used to define anemia thresholds.
hemoglobin_g_dl	Numeric. Hemoglobin level in g/dL. Anemia (<13 g/dL in men, <12 g/dL in women) adds +3 points.
egfr_ml_min	Numeric. Estimated Glomerular Filtration Rate (eGFR) in mL/min/1.73m^2. Severe renal disease (<30 mL/min) adds +3 points.
prior_bleeding	Numeric (0 or 1). History of prior hemorrhage diagnosis. (1 = Yes, +1 point).
hypertension	Numeric (0 or 1). History of hypertension. (1 = Yes, +1 point).

Value

A list containing:

ATRIA_Score	The calculated risk score (Range 0-10).
Risk_Category	Classification (Low: 0-3, Intermediate: 4, High: >4).
Annual_Major_Bleeding_Risk	Estimated annual rate of major hemorrhage.

References

Fang MC, Go AS, Chang Y, et al. A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study. J Am Coll Cardiol. 2011;58(4):395-401. doi:10.1016/j.jacc.2011.03.031

Examples

# Example 1: High Risk
# 80yo Male (+2), Hgb 11 (+3), eGFR 25 (+3), No Bleed, HTN (+1)
# Score = 9
atria_bleeding_risk(80, "male", 11, 25, 0, 1)

# Example 2: Low Risk
# 65yo Female (0), Hgb 13 (0), eGFR 60 (0), No Bleed, No HTN
# Score = 0
atria_bleeding_risk(65, "female", 13, 60, 0, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.