berlin_ards_criteria: Berlin Criteria for Acute Respiratory Distress Syndrome...

In cliot: Clinical Indices and Outcomes Tools

Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS)

Description

Applies the Berlin Definition to diagnostic criteria for ARDS. It evaluates timing, chest imaging, origin of edema, and oxygenation status to classify patients into Mild, Moderate, or Severe ARDS.

Usage

berlin_ards_criteria(timing_within_1_week, bilateral_opacities,
                     edema_not_cardiac, pao2_fio2_ratio, peep_or_cpap)

Arguments

timing_within_1_week	Numeric (0 or 1). Onset within 1 week of a known clinical insult or new/worsening respiratory symptoms. (1 = Yes).
bilateral_opacities	Numeric (0 or 1). Bilateral opacities on CXR or CT not fully explained by effusions, lobar/lung collapse, or nodules. (1 = Yes).
edema_not_cardiac	Numeric (0 or 1). Respiratory failure not fully explained by cardiac failure or fluid overload. (1 = Yes).
pao2_fio2_ratio	Numeric. Ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (PaO2/FiO2) in mmHg. Mild: 200 < Ratio <= 300. Moderate: 100 < Ratio <= 200. Severe: Ratio <= 100.
peep_or_cpap	Numeric. Positive End-Expiratory Pressure (PEEP) or Continuous Positive Airway Pressure (CPAP) in cmH2O. Must be >= 5 for diagnosis.

Value

A list containing:

Classification	The severity class (Mild, Moderate, Severe, or Not ARDS).
Predicted_Mortality	Estimated mortality risk based on the Berlin derivation cohort.
Failure_Reasons	List of specific criteria that were not met.

References

The ARDS Definition Task Force. Acute Respiratory Distress Syndrome: The Berlin Definition. JAMA. 2012;307(23):2526-2533. doi:10.1001/jama.2012.5669

Examples

# Example 1: Severe ARDS
# Acute onset, Bilateral infiltrates, Non-cardiac, PF Ratio 80, PEEP 10
berlin_ards_criteria(1, 1, 1, 80, 10)

# Example 2: Not ARDS (PF Ratio too high)
# PF Ratio 350
berlin_ards_criteria(1, 1, 1, 350, 5)

# Example 3: Not ARDS (PEEP too low)
# PEEP 2
berlin_ards_criteria(1, 1, 1, 150, 2)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.