cerebral_perfusion_pressure: Cerebral Perfusion Pressure (CPP)

In cliot: Clinical Indices and Outcomes Tools

Cerebral Perfusion Pressure (CPP)

Description

Calculates Cerebral Perfusion Pressure (CPP), defined as the net pressure gradient causing cerebral blood flow to the brain. It is calculated by subtracting the Intracranial Pressure (ICP) from the Mean Arterial Pressure (MAP). Maintenance of adequate CPP is critical in the management of Traumatic Brain Injury (TBI) to prevent ischemia.

Usage

cerebral_perfusion_pressure(mean_arterial_pressure, intracranial_pressure)

Arguments

mean_arterial_pressure	Numeric. The Mean Arterial Pressure (MAP) in mmHg.
intracranial_pressure	Numeric. The Intracranial Pressure (ICP) in mmHg.

Value

A list containing:

CPP_mmHg	The calculated Cerebral Perfusion Pressure.
Interpretation	Clinical context based on Brain Trauma Foundation guidelines (Target 60-70 mmHg).

References

Carney N, Totten AM, O'Reilly C, et al. Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition. Neurosurgery. 2017;80(1):6-15. doi:10.1227/NEU.0000000000001432

Examples

# Example 1: Normal Target
# MAP 85, ICP 15
# CPP = 70 mmHg
cerebral_perfusion_pressure(85, 15)

# Example 2: Ischemic Risk
# MAP 60, ICP 25
# CPP = 35 mmHg
cerebral_perfusion_pressure(60, 25)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.