cockcroft_gault_crcl: Creatinine Clearance (Cockcroft-Gault Equation)

In cliot: Clinical Indices and Outcomes Tools

Creatinine Clearance (Cockcroft-Gault Equation)

Description

Calculates Creatinine Clearance (CrCl) using the Cockcroft-Gault equation. This implementation replicates the MDCalc logic for weight selection: - BMI < 18.5: Uses Actual Body Weight. - BMI 18.5 - 24.9: Uses Ideal Body Weight. - BMI >= 25: Uses Adjusted Body Weight. If height is not provided, it defaults to using Actual Body Weight.

Usage

cockcroft_gault_crcl(sex, age, creatinine, weight_kg, height_cm = NULL,
                     creatinine_units = "mg/dL")

Arguments

sex	String. Patient sex ("Male" or "Female").
age	Numeric. Patient age in years.
creatinine	Numeric. Serum creatinine level.
weight_kg	Numeric. Actual body weight in kilograms.
height_cm	Numeric (Optional). Height in centimeters. Required to calculate BMI/IBW for the specific weight selection logic.
creatinine_units	String. Units for creatinine. Options: "mg/dL" (default) or "micromol/L".

Value

A list containing:

CrCl_mL_min	The estimated Creatinine Clearance.
Weight_Used_kg	The specific weight value used in the calculation.
Method	Description of which weight formula was selected (Actual, Ideal, or Adjusted).

References

Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41. doi:10.1159/000180580 Winter MA, Guhr KN, Berg GM. Impact of various body weights and serum creatinine concentrations on the bias and accuracy of the Cockcroft-Gault equation. Pharmacotherapy. 2012;32(7):604-612.

Examples

# Example 1: Normal Weight Male
# Age 54, Cr 1.2, Wt 75kg, Ht 180cm (BMI ~23 -> Uses IBW)
cockcroft_gault_crcl("male", 54, 1.2, 75, 180)

# Example 2: Obese Female
# Age 65, Cr 0.9, Wt 90kg, Ht 160cm (BMI ~35 -> Uses Adjusted BW)
cockcroft_gault_crcl("female", 65, 0.9, 90, 160)

# Example 3: No Height Provided (Defaults to Actual Weight)
cockcroft_gault_crcl("male", 40, 1.0, 80)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.