damico_prostate_risk: D'Amico Risk Classification for Prostate Cancer

In cliot: Clinical Indices and Outcomes Tools

D'Amico Risk Classification for Prostate Cancer

Description

Calculates the D'Amico Risk Classification for prostate cancer. This system stratifies patients into Low, Intermediate, or High risk of biochemical recurrence following localized treatment (surgery or radiation) based on PSA level, Gleason score, and Clinical T stage.

Usage

damico_prostate_risk(psa, gleason_score, clinical_t_stage)

Arguments

psa	Numeric. Prostate-Specific Antigen level in ng/mL.
gleason_score	Numeric. Total Gleason Score (sum of primary and secondary patterns).
clinical_t_stage	String. Clinical Tumor (T) Stage. Accepted values: "t1", "t1a", "t1b", "t1c", "t2a", "t2b", "t2c", "t3", "t3a", "t3b", "t4".

Value

A list containing:

Risk_Classification

The determined risk group: "Low Risk": PSA < 10 AND Gleason <= 6 AND T-stage T1-T2a. "Intermediate Risk": PSA 10-20 OR Gleason 7 OR T-stage T2b. "High Risk": PSA > 20 OR Gleason >= 8 OR T-stage >= T2c.

References

D'Amico AV, Whittington R, Malkowicz SB, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA. 1998;280(11):969-974. doi:10.1001/jama.280.11.969

Examples

# Example 1: High Risk
# PSA 8 (Low), Gleason 8 (High), T2a (Low)
# Result = High Risk
damico_prostate_risk(8, 8, "t2a")

# Example 2: Low Risk
# PSA 5, Gleason 6, T1c
# Result = Low Risk
damico_prostate_risk(5, 6, "t1c")

cliot documentation built on Dec. 1, 2025, 1:06 a.m.