fibrotic_nash_index: Fibrotic NASH Index (FNI)

In cliot: Clinical Indices and Outcomes Tools

Fibrotic NASH Index (FNI)

Description

Calculates the Fibrotic NASH Index (FNI) to predict the presence of advanced fibrosis in patients with Nonalcoholic Steatohepatitis (NASH). This simple index uses three common laboratory values: AST, HDL cholesterol, and HbA1c.

Usage

fibrotic_nash_index(ast, hdl_cholesterol, hba1c)

Arguments

ast	Numeric. Aspartate Aminotransferase level (U/L).
hdl_cholesterol	Numeric. High-Density Lipoprotein Cholesterol level (mg/dL).
hba1c	Numeric. Hemoglobin A1c percentage.

Value

A list containing:

FNI_Score	The calculated risk score (probability between 0 and 1).
Risk_Category	Classification (Low < 0.10, Intermediate 0.10-0.33, High > 0.33).
Interpretation	Clinical meaning of the risk category.

References

Loomba R, et al. Fibrotic NASH Index: A Simple Model to Predict Advanced Fibrosis in Patients With Nonalcoholic Steatohepatitis. Hepatology. 2019.

Examples

# Example 1: High Risk
# AST 80, HDL 30, HbA1c 8.5
fibrotic_nash_index(80, 30, 8.5)

# Example 2: Low Risk
# AST 20, HDL 60, HbA1c 5.0
fibrotic_nash_index(20, 60, 5.0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.