flipi_score: Follicular Lymphoma International Prognostic Index (FLIPI)

In cliot: Clinical Indices and Outcomes Tools

Follicular Lymphoma International Prognostic Index (FLIPI)

Description

Calculates the FLIPI score to predict overall survival in patients with follicular lymphoma. The score uses five adverse prognostic factors: Age >= 60, Ann Arbor Stage III-IV, Hemoglobin < 12 g/dL, Elevated LDH, and > 4 Nodal sites involved.

Usage

flipi_score(age, ann_arbor_stage, hemoglobin_g_dl, ldh_elevated,
            num_nodal_sites)

Arguments

age	Numeric. Patient age in years. (>= 60 years adds +1 point).
ann_arbor_stage	Numeric (1-4). Ann Arbor Stage. (Stage III or IV adds +1 point).
hemoglobin_g_dl	Numeric. Hemoglobin level in g/dL. (< 12 g/dL adds +1 point).
ldh_elevated	Numeric (0 or 1). Serum LDH greater than the upper limit of normal. (1 = Yes, +1 point).
num_nodal_sites	Numeric. Count of involved nodal areas. (> 4 sites adds +1 point).

Value

A list containing:

FLIPI_Score	The calculated score (Range 0-5).
Risk_Group	Classification (Low 0-1, Intermediate 2, High >=3).
Est_10_Year_Survival	Estimated 10-year overall survival percentage.

References

Solal-Céligny P, Roy P, Colombat P, et al. Follicular lymphoma international prognostic index. Blood. 2004;104(5):1258-1265. doi:10.1182/blood-2003-12-4434

Examples

# Example 1: High Risk
# 65yo (+1), Stage IV (+1), Hb 11 (+1), Normal LDH (0), 3 Nodes (0)
# Score = 3
flipi_score(65, 4, 11.0, 0, 3)

# Example 2: Low Risk
# 50yo (0), Stage II (0), Hb 13 (0), High LDH (+1), 2 Nodes (0)
# Score = 1
flipi_score(50, 2, 13.0, 1, 2)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.