fong_crs_score: Fong Clinical Risk Score (CRS) for Colorectal Cancer...

In cliot: Clinical Indices and Outcomes Tools

Fong Clinical Risk Score (CRS) for Colorectal Cancer Recurrence

Description

Calculates the Fong Clinical Risk Score (CRS) to predict recurrence and survival in patients undergoing resection of hepatic metastases from colorectal cancer. The score is based on five clinical criteria: nodal status of the primary tumor, disease-free interval, number of hepatic tumors, preoperative CEA level, and size of the largest hepatic tumor.

Usage

fong_crs_score(nodal_status_primary, disease_free_interval_lt_12mo,
               num_tumors_gt_1, preop_cea_gt_200, largest_tumor_gt_5cm)

Arguments

nodal_status_primary	Numeric (0 or 1). Node-positive primary tumor. (1 = Yes, +1 point).
disease_free_interval_lt_12mo	Numeric (0 or 1). Disease-free interval from primary diagnosis to discovery of liver metastases < 12 months. (1 = Yes, +1 point).
num_tumors_gt_1	Numeric (0 or 1). Number of hepatic tumors > 1. (1 = Yes, +1 point).
preop_cea_gt_200	Numeric (0 or 1). Preoperative Carcinoembryonic Antigen (CEA) level > 200 ng/mL. (1 = Yes, +1 point).
largest_tumor_gt_5cm	Numeric (0 or 1). Size of the largest hepatic tumor > 5 cm. (1 = Yes, +1 point).

Value

A list containing:

Fong_Score	The calculated risk score (Range 0-5).
Risk_Group	Classification (Low, Intermediate, High).
Est_5_Year_Survival	Estimated 5-year survival probability.
Median_Survival	Estimated median survival time in months.

References

Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg. 1999;230(3):309-318. doi:10.1097/00000658-199909000-00004

Examples

# Example 1: High Risk
# Node+ Primary, DFI < 12mo, Multiple tumors, CEA 50, Size 3cm
# Score = 1 + 1 + 1 + 0 + 0 = 3
fong_crs_score(1, 1, 1, 0, 0)

# Example 2: Low Risk
# Node Negative, DFI > 12mo, Single tumor, CEA < 200, Size < 5cm
# Score = 0
fong_crs_score(0, 0, 0, 0, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.