glasgow_alcoholic_hepatitis_score: Glasgow Alcoholic Hepatitis Score (GAHS)

In cliot: Clinical Indices and Outcomes Tools

Glasgow Alcoholic Hepatitis Score (GAHS)

Description

Calculates the Glasgow Alcoholic Hepatitis Score (GAHS) to predict the prognosis of patients with alcoholic hepatitis. The score ranges from 5 to 12, based on Age, White Blood Cell count, Urea, Prothrombin Time (INR), and Bilirubin. A score of 9 or higher indicates a poor prognosis and may guide the use of corticosteroids (specifically for patients with a discriminant function >= 32).

Usage

glasgow_alcoholic_hepatitis_score(age, wbc_count, urea, pt_inr, bilirubin,
                                  bilirubin_units = "mg/dL", urea_units = "mg/dL")

Arguments

age	Numeric. Patient age in years. (<50: 1 pt, >=50: 2 pts).
wbc_count	Numeric. White Blood Cell count in 10^9/L. (<15: 1 pt, >=15: 2 pts).
urea	Numeric. Blood Urea Nitrogen (BUN) or Urea. (<5 mmol/L: 1 pt, >=5 mmol/L: 2 pts).
pt_inr	Numeric. INR ratio. (<1.5: 1 pt, 1.5-2.0: 2 pts, >=2.0: 3 pts).
bilirubin	Numeric. Total Bilirubin level. (<125 umol/L: 1 pt, 125-250: 2 pts, >=250: 3 pts).
bilirubin_units	String. Units for bilirubin. "mg/dL" (default) or "umol/L".
urea_units	String. Units for urea input. "mg/dL" (default, assumed BUN) or "mmol/L".

Value

A list containing:

GAHS_Score	The calculated score (Range 5-12).
Survival_28_Day	Estimated 28-day survival percentage.
Survival_84_Day	Estimated 84-day survival percentage.

References

Forrest EH, Evans CD, Stewart S, et al. Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score. Gut. 2005;54(8):1174-1179. doi:10.1136/gut.2004.050781

Examples

# Example 1: High Risk (Score >= 9)
# Age 55 (2), WBC 18 (2), BUN 30 (~10mmol) (2), INR 2.2 (3), Bili 15 (~256umol) (3)
# Score = 2+2+2+3+3 = 12
glasgow_alcoholic_hepatitis_score(55, 18, 30, 2.2, 15)

# Example 2: Low Risk (Score < 9)
# Age 40 (1), WBC 10 (1), BUN 10 (~3.5mmol) (1), INR 1.2 (1), Bili 2 (~34umol) (1)
# Score = 5
glasgow_alcoholic_hepatitis_score(40, 10, 10, 1.2, 2)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.