mdrd_gfr_equation: MDRD GFR Equation (IDMS-Traceable)

In cliot: Clinical Indices and Outcomes Tools

MDRD GFR Equation (IDMS-Traceable)

Description

Calculates the estimated Glomerular Filtration Rate (eGFR) using the Modification of Diet in Renal Disease (MDRD) Study equation. This version uses the IDMS-traceable formula (standardized serum creatinine). Note: The MDRD equation has largely been superseded by CKD-EPI for general use but remains relevant in certain clinical contexts or historical data comparisons.

Usage

mdrd_gfr_equation(creatinine, age, sex, race, creatinine_units = "mg/dL")

Arguments

creatinine	Numeric. Serum Creatinine level.
age	Numeric. Patient age in years.
sex	String. Patient sex ("Male" or "Female").
race	String. Patient race ("black" or "other"). The equation applies a correction factor (x1.212) for African American patients.
creatinine_units	String. Units for creatinine input. Options: "mg/dL" (default) or "umol/L" (or "micromol/L").

Value

A list containing:

MDRD_GFR	The estimated GFR in mL/min/1.73m^2.
CKD_Stage	Staging classification based on the calculated GFR.

References

Levey AS, Coresh J, Greene T, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006;145(4):247-254. doi:10.7326/0003-4819-145-4-200608150-00004

Examples

# Example 1: Healthy Adult
# Cr 0.9, 40yo Male, Non-Black
# GFR = 175 * (0.9)^-1.154 * (40)^-0.203 = ~98
mdrd_gfr_equation(0.9, 40, "male", "other")

# Example 2: Chronic Kidney Disease
# Cr 2.5, 65yo Female, Black
# GFR = 175 * (2.5)^-1.154 * (65)^-0.203 * 0.742 * 1.212 = ~23
mdrd_gfr_equation(2.5, 65, "female", "black")

cliot documentation built on Dec. 1, 2025, 1:06 a.m.