mehran_score_cin: Mehran Score for Post-PCI Contrast-Induced Nephropathy (CIN)

In cliot: Clinical Indices and Outcomes Tools

Mehran Score for Post-PCI Contrast-Induced Nephropathy (CIN)

Description

Calculates the Mehran Risk Score to predict the risk of Contrast-Induced Nephropathy (CIN) and the need for dialysis following Percutaneous Coronary Intervention (PCI). The score uses clinical factors (hypotension, IABP, CHF, age, diabetes, anemia), contrast volume, and renal function (Serum Creatinine or eGFR).

Usage

mehran_score_cin(hypotension, intraaortic_balloon_pump, congestive_heart_failure,
                 age_gt_75, diabetes, anemia, contrast_volume_cc,
                 serum_creatinine_mg_dl = NULL, egfr_ml_min = NULL)

Arguments

hypotension	Numeric (0 or 1). SBP < 80 mmHg for > 1 hour requiring inotropes or IABP support. (1 = Yes, +5 pts).
intraaortic_balloon_pump	Numeric (0 or 1). Use of IABP. (1 = Yes, +5 pts).
congestive_heart_failure	Numeric (0 or 1). CHF Class III/IV or history of pulmonary edema. (1 = Yes, +5 pts).
age_gt_75	Numeric (0 or 1). Age > 75 years. (1 = Yes, +4 pts).
diabetes	Numeric (0 or 1). History of diabetes. (1 = Yes, +3 pts).
anemia	Numeric (0 or 1). Baseline hematocrit < 39% for men or < 36% for women. (1 = Yes, +3 pts).
contrast_volume_cc	Numeric. Total volume of contrast media used in cc (mL). (1 point per 100 cc).
serum_creatinine_mg_dl	Numeric (Optional). Baseline Serum Creatinine in mg/dL. (> 1.5 mg/dL adds 4 pts). Note: Original score used SCr; updated versions often incorporate eGFR.
egfr_ml_min	Numeric (Optional). Estimated GFR in mL/min/1.73m^2. Used if Serum Creatinine is not provided for more granular scoring (20-40: +4, 40-60: +2, <20: +6).

Value

A list containing:

Mehran_Score	The calculated risk score (Range 0-~30+).
Risk_Class	Classification (Low, Moderate, High, Very High).
Risk_CIN	Estimated probability of developing CIN (>= 25% rise or >= 0.5 mg/dL increase in SCr).
Risk_Dialysis	Estimated probability of requiring dialysis.

References

Mehran R, Aymong ED, Nikolsky E, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol. 2004;44(7):1393-1399. doi:10.1016/j.jacc.2004.06.068

Examples

# Example 1: High Risk
# Hypotension (+5), Diabetes (+3), Contrast 250cc (+2), SCr 1.8 (+4)
# Score = 14
mehran_score_cin(1, 0, 0, 0, 1, 0, 250, serum_creatinine_mg_dl = 1.8)

# Example 2: Low Risk
# Age 50 (0), Contrast 100cc (+1), Normal SCr (0), No other factors
# Score = 1
mehran_score_cin(0, 0, 0, 0, 0, 0, 100, serum_creatinine_mg_dl = 0.9)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.