murray_lung_injury_score: Murray Score for Acute Lung Injury

In cliot: Clinical Indices and Outcomes Tools

Murray Score for Acute Lung Injury

Description

Calculates the Murray Lung Injury Score (LIS) to assess the severity of Acute Respiratory Distress Syndrome (ARDS). The score averages four components: Hypoxemia (PaO2/FiO2), PEEP, Respiratory Compliance, and Chest X-ray infiltration.

Usage

murray_lung_injury_score(pao2_fio2_ratio, peep, respiratory_compliance,
                         cxr_quadrants)

Arguments

pao2_fio2_ratio	Numeric. Ratio of arterial oxygen partial pressure to fractional inspired oxygen (PaO2/FiO2). >=300: 0 pts. 225-299: 1 pt. 175-224: 2 pts. 100-174: 3 pts. <100: 4 pts.
peep	Numeric. Positive End-Expiratory Pressure (cmH2O). <=5: 0 pts. 6-8: 1 pt. 9-11: 2 pts. 12-14: 3 pts. >=15: 4 pts.
respiratory_compliance	Numeric. Respiratory system compliance (mL/cmH2O). Typically calculated as Tidal Volume / (Plateau Pressure - PEEP). >=80: 0 pts. 60-79: 1 pt. 40-59: 2 pts. 20-39: 3 pts. <=19: 4 pts.
cxr_quadrants	Numeric (0-4). Number of quadrants showing alveolar consolidation on Chest X-ray. 0: 0 pts. 1: 1 pt. 2: 2 pts. 3: 3 pts. 4: 4 pts.

Value

A list containing:

Murray_Score	The calculated Lung Injury Score (average of the 4 components, Range 0-4).
Severity_Assessment	Interpretation (No Injury = 0, Mild-Moderate 0.1-2.5, Severe > 2.5).
Subscores	Individual points assigned to each component.

References

Murray JF, Matthay MA, Luce JM, Flick MR. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988;138(3):720-723. doi:10.1164/ajrccm/138.3.720

Examples

# Example 1: Severe ARDS
# PF 80 (4 pts), PEEP 16 (4 pts), Compliance 18 (4 pts), CXR 4 quads (4 pts)
# Average = 16 / 4 = 4
murray_lung_injury_score(80, 16, 18, 4)

# Example 2: Mild Injury
# PF 250 (1 pt), PEEP 8 (1 pt), Compliance 50 (2 pts), CXR 1 quad (1 pt)
# Average = 5 / 4 = 1.25
murray_lung_injury_score(250, 8, 50, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.