myxedema_coma_score: Myxedema Coma Diagnostic Score

In cliot: Clinical Indices and Outcomes Tools

Myxedema Coma Diagnostic Score

Description

Calculates the diagnostic score for myxedema coma. This tool aggregates clinical and laboratory findings (thermoregulation, CNS status, GI symptoms, cardiovascular dysfunction, metabolic disturbances, and precipitating events) to assess the likelihood of myxedema coma in patients with severe hypothyroidism.

Usage

myxedema_coma_score(temp_c, cns_status, gi_symptoms, precipitating_event,
                    bradycardia, ecg_changes, hypotension, hyponatremia,
                    hypoglycemia, hypoxemia_hypercapnia)

Arguments

temp_c	Numeric. Body temperature in degrees Celsius. (>35: 0 pts, 32-35: 10 pts, <32: 20 pts).
cns_status	String. Central Nervous System status. Options: "absent" (0 pts), "drowsy_lethargic" (10 pts), "obtunded" (15 pts), "stupor_coma" (20 pts).
gi_symptoms	String. Gastrointestinal symptoms. Options: "absent" (0 pts), "anorexia_pain_constipation" (5 pts), "decreased_motility_ileus" (10 pts).
precipitating_event	Numeric (0 or 1). Presence of a precipitating event (e.g., infection, surgery, drug exposure). (1 = Yes, +10 pts).
bradycardia	Numeric (0 or 1). Bradycardia present. (1 = Yes, +10 pts).
ecg_changes	Numeric (0 or 1). ECG changes present (e.g., low voltage, prolonged QT, heart block). (1 = Yes, +10 pts).
hypotension	Numeric (0 or 1). Hypotension or cardiogenic shock present. (1 = Yes, +10 pts).
hyponatremia	Numeric (0 or 1). Hyponatremia present. (1 = Yes, +10 pts).
hypoglycemia	Numeric (0 or 1). Hypoglycemia present. (1 = Yes, +10 pts).
hypoxemia_hypercapnia	Numeric (0 or 1). Hypoxemia or hypercapnia present. (1 = Yes, +10 pts).

Value

A list containing:

Diagnostic_Score	The calculated total score.
Interpretation	Diagnostic likelihood (Unlikely <25, Suggestive 25-59, Diagnostic >=60).

References

Popoveniuc G, Chandra T, Sud A, et al. A diagnostic scoring system for myxedema coma. Endocr Pract. 2014;20(8):808-817. doi:10.4158/EP13303.OR

Examples

# Example 1: Diagnostic (Score 70)
# Temp 30C (20), Coma (20), Ileus (10), Precipitant (10), Bradycardia (10)
myxedema_coma_score(30, "stupor_coma", "decreased_motility_ileus", 1, 1, 0, 0, 0, 0, 0)

# Example 2: Suggestive (Score 30)
# Temp 34C (10), Lethargic (10), Hypoglycemia (10)
myxedema_coma_score(34, "drowsy_lethargic", "absent", 0, 0, 0, 0, 0, 1, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.