osiris_osteoporosis_score: Osteoporosis Index of Risk (OSIRIS)

In cliot: Clinical Indices and Outcomes Tools

Osteoporosis Index of Risk (OSIRIS)

Description

Calculates the OSIRIS score to stratify the risk of osteoporosis in postmenopausal women. The score utilizes four simple clinical variables: age, body weight, current hormone replacement therapy (HRT) use, and history of prior low-impact fracture. It aids in selecting women for Bone Mineral Density (BMD) testing.

Usage

osiris_osteoporosis_score(age, weight_kg, history_fracture, estrogen_therapy)

Arguments

age	Numeric. Patient age in years.
weight_kg	Numeric. Patient weight in kilograms.
history_fracture	Numeric (0 or 1). History of previous low-impact fracture (e.g., wrist, spine, hip) occurring after age 45. (1 = Yes, -2 points).
estrogen_therapy	Numeric (0 or 1). Current use of Estrogen Replacement Therapy / Hormone Replacement Therapy (HRT). (1 = Yes, +2 points).

Value

A list containing:

OSIRIS_Score	The calculated index score.
Risk_Category	Classification (High Risk < 1, Medium Risk 1-3, Low Risk > 3).
Recommendation	Guidance regarding BMD testing.

References

Sedrani O, et al. Accelerating the diagnosis of osteoporosis. The OSIRIS rule. (Osteoporosis Index of Risk). 2002.

Examples

# Example 1: High Risk
# 75yo, 50kg, Prior Fracture (+2 negative points), No HRT
# Base = (50-75)*0.2 = -5. Fx = -2. Total = -7.
osiris_osteoporosis_score(75, 50, 1, 0)

# Example 2: Low Risk
# 55yo, 70kg, No Fracture, On HRT (+2 positive points)
# Base = (70-55)*0.2 = 3. HRT = +2. Total = 5.
osiris_osteoporosis_score(55, 70, 0, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.