pompe_c_score: POMPE-C Tool for Pulmonary Embolism Mortality in Cancer

In cliot: Clinical Indices and Outcomes Tools

POMPE-C Tool for Pulmonary Embolism Mortality in Cancer

Description

Calculates the POMPE-C score to stratify the risk of 30-day all-cause mortality in patients with active cancer and acute symptomatic pulmonary embolism (PE). The score uses clinical variables including vital signs, physical exam findings, and do-not-resuscitate (DNR) status.

Usage

pompe_c_score(altered_mental_status, dnr_status, oxygen_saturation, weight_kg,
              respiratory_rate, heart_rate, unilateral_leg_swelling)

Arguments

altered_mental_status	Numeric (0 or 1). Presence of altered mental status (disorientation, stupor, coma). (1 = Yes, +18 pts).
dnr_status	Numeric (0 or 1). Do Not Resuscitate (DNR) status established. (1 = Yes, +13 pts).
oxygen_saturation	Numeric. Oxygen saturation on room air (%). (< 90% adds 8 pts).
weight_kg	Numeric. Body weight in kilograms. (< 70 kg adds 6 pts).
respiratory_rate	Numeric. Respiratory rate in breaths per minute. (>= 24 bpm adds 6 pts).
heart_rate	Numeric. Heart rate in beats per minute. (>= 100 bpm adds 5 pts).
unilateral_leg_swelling	Numeric (0 or 1). Clinical signs of Deep Vein Thrombosis (unilateral leg swelling). (1 = Yes, -3 pts).

Value

A list containing:

POMPE_C_Score	The calculated risk score (Range -3 to 56).
Risk_Category	Classification (Low <= 5, Intermediate 6-19, High >= 20).
Est_30_Day_Mortality	Estimated 30-day mortality percentage range based on derivation and validation cohorts.

References

Sanchez O, Carmona L, Nieto JA, et al. Predicting 30-day mortality in patients with cancer and acute symptomatic pulmonary embolism: The POMPE-C tool. J Thromb Haemost. 2014;12(11):1833-1840. doi:10.1111/jth.12716

Examples

# Example 1: High Risk
# DNR (1), SpO2 88%, Weight 60kg, HR 110
# Score = 13 + 8 + 6 + 5 = 32
pompe_c_score(0, 1, 88, 60, 20, 110, 0)

# Example 2: Low Risk
# No risk factors, Leg Swelling present
# Score = -3
pompe_c_score(0, 0, 98, 80, 16, 80, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.