reids_colposcopic_index: Reid's Colposcopic Index (RCI)

View source: R/neelpackage.R

reids_colposcopic_indexR Documentation

Reid's Colposcopic Index (RCI)

Description

Calculates the Reid's Colposcopic Index (RCI) score to grade the severity of premalignant cervical lesions during colposcopy. The score is based on four colposcopic signs: lesion margin, color of acetowhitening, vascular patterns, and iodine staining response.

Usage

reids_colposcopic_index(lesion_margin, acetowhitening_color, vascular_patterns,
                        iodine_staining)

Arguments

lesion_margin

Numeric (0-2). Characteristics of the lesion margin. 0: Condylomatous or micropapillary contour; indistinct, flocculated, or feathered margins; jagged/angular lesions; satellite lesions beyond the transformation zone. 1: Regular lesions with smooth, straight outlines. 2: Rolled, peeling edges; internal borders between areas of differing appearance.

acetowhitening_color

Numeric (0-2). Color of the lesion after acetic acid application. 0: Shiny, snow-white; indistinct acetowhitening; semitransparent. 1: Shiny, off-white; intermediate white; gray-white. 2: Dull, oyster gray; dense/opaque acetowhitening.

vascular_patterns

Numeric (0-2). Characteristics of blood vessels within the lesion. 0: Uniform, fine-caliber vessels; poorly formed patterns; nondilated capillary loops. 1: Absence of surface vessels after acetic acid soaking. 2: Definite, coarse punctation or mosaicism; dilated vessels arranged in well-defined patterns.

iodine_staining

Numeric (0-2). Response to Lugol's iodine solution. 0: Positive iodine uptake (mahogany brown); or negative uptake (mustard yellow) in a lesion scoring <=2 points on the first three criteria. 1: Partial iodine uptake; variegated/tortoise-shell appearance. 2: Negative iodine uptake (mustard yellow) in a lesion scoring >=3 points on the first three criteria.

Value

A list containing:

RCI_Score

The calculated total score (Range 0-8).

Predicted_Histology

Predicted histologic grade (Low, Intermediate, or High grade).

References

Reid R, Scalzi P. Genital warts and cervical cancer. VII. An improved colposcopic index for differentiating benign papillomaviral infections from high-grade cervical intraepithelial neoplasia. Am J Obstet Gynecol. 1985;153(6):611-618. doi:10.1016/0002-9378(85)90245-2

Examples


# Example 1: High Grade Lesion
# Rolled edges (2), Dull gray (2), Coarse mosaic (2), Negative iodine (2)
# Score = 8
reids_colposcopic_index(2, 2, 2, 2)

# Example 2: Low Grade Lesion
# Irregular margin (0), Snow white (0), Fine vessels (0), Positive iodine (0)
# Score = 0
reids_colposcopic_index(0, 0, 0, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.