resp_ecmo_score: RESP Score for ECMO Survival Prediction

In cliot: Clinical Indices and Outcomes Tools

RESP Score for ECMO Survival Prediction

Description

Calculates the Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) score. This tool predicts in-hospital survival for adult patients undergoing ECMO for severe Acute Respiratory Distress Syndrome (ARDS). It stratifies patients into five risk classes based on 12 pre-ECMO variables.

Usage

resp_ecmo_score(age, immunocompromised, mv_duration_hours, diagnosis_category,
                cns_dysfunction, acute_infection_non_pulm, neuromuscular_blockade,
                nitric_oxide_use, bicarbonate_use, cardiac_arrest, paco2_mmhg,
                pip_cmh2o)

Arguments

age	Numeric. Patient age in years. 18-49: 0 pts. 50-59: -2 pts. >=60: -3 pts.
immunocompromised	Numeric (0 or 1). Immunocompromised status (hematological malignancy, solid tumor, solid organ transplant, HIV, cirrhosis). (1 = Yes, -2 pts).
mv_duration_hours	Numeric. Duration of mechanical ventilation prior to ECMO initiation in hours. < 48 hours: +3 pts. 48 hours - 7 days: +1 pt. > 7 days: 0 pts.
diagnosis_category	String. Primary acute respiratory diagnosis. "viral_pneumonia", "bacterial_pneumonia", "aspiration_pneumonitis", "trauma_burn": +3 pts. "asthma": +11 pts. "other_acute_respiratory" (e.g., inhalation injury, alveolar hemorrhage): +1 pt. "chronic_non_respiratory" (e.g., chronic lung disease, non-respiratory cause): 0 pts.
cns_dysfunction	Numeric (0 or 1). Central nervous system dysfunction (neurotrauma, stroke, encephalopathy, seizure). (1 = Yes, -7 pts).
acute_infection_non_pulm	Numeric (0 or 1). Acute associated non-pulmonary infection. (1 = Yes, -3 pts).
neuromuscular_blockade	Numeric (0 or 1). Use of neuromuscular blockade agents before ECMO. (1 = Yes, +1 pt).
nitric_oxide_use	Numeric (0 or 1). Use of Nitric Oxide before ECMO. (1 = Yes, -1 pt).
bicarbonate_use	Numeric (0 or 1). Use of Bicarbonate infusion before ECMO. (1 = Yes, -2 pts).
cardiac_arrest	Numeric (0 or 1). Pre-ECMO cardiac arrest. (1 = Yes, -2 pts).
paco2_mmhg	Numeric. Partial pressure of arterial carbon dioxide in mmHg. (>= 75 mmHg: -2 pts).
pip_cmh2o	Numeric. Peak Inspiratory Pressure in cmH2O. (>= 42 cmH2O: -2 pts).

Value

A list containing:

RESP_Score	The calculated total score (Range -22 to 15).
Risk_Class	Risk classification (Class I to V).
Est_Hospital_Survival	Estimated in-hospital survival percentage.

References

Schmidt M, Bailey M, Sheldrake J, et al. Predicting survival for severe ARDS patients on extracorporeal membrane oxygenation: the RESP score. Am J Respir Crit Care Med. 2014;189(11):1374-1382. doi:10.1164/rccm.201311-2023OC

Examples

# Example 1: Good Prognosis (Class I)
# 30yo (0), Asthma (+11), MV 10h (+3), NMB (+1)
# Score = 15
resp_ecmo_score(30, 0, 10, "asthma", 0, 0, 1, 0, 0, 0, 40, 30)

# Example 2: Poor Prognosis (Class IV)
# 65yo (-3), Bacterial PNA (+3), MV 8 days (0), Immuno (-2), CNS Dysfx (-7)
# Score = -9
resp_ecmo_score(65, 1, 200, "bacterial_pneumonia", 1, 0, 0, 0, 0, 0, 40, 30)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.