rifle_criteria_aki: RIFLE Criteria for Acute Kidney Injury (AKI)

In cliot: Clinical Indices and Outcomes Tools

RIFLE Criteria for Acute Kidney Injury (AKI)

Description

Calculates the RIFLE classification (Risk, Injury, Failure, Loss, End-stage) for Acute Kidney Injury. The classification is based on the worst of either serum creatinine/GFR criteria or urine output criteria. 'Loss' and 'End-stage' are outcome categories determined by the duration of kidney failure, which are not calculated by this function (typically >4 weeks and >3 months, respectively).

Usage

rifle_criteria_aki(baseline_creatinine, current_creatinine, gfr_decrease_percent,
                   urine_output_ml_kg_hr, urine_output_duration_hours,
                   anuria_duration_hours)

Arguments

baseline_creatinine	Numeric. Baseline serum creatinine level (mg/dL).
current_creatinine	Numeric. Current serum creatinine level (mg/dL).
gfr_decrease_percent	Numeric. Percentage decrease in GFR (if known). Set to 0 if unknown. (25% = Risk, 50% = Injury, 75% = Failure).
urine_output_ml_kg_hr	Numeric. Urine output rate in mL/kg/hr.
urine_output_duration_hours	Numeric. Duration of decreased urine output in hours.
anuria_duration_hours	Numeric. Duration of anuria in hours.

Value

A list containing:

RIFLE_Class	The final determined RIFLE class (Risk, Injury, Failure, or No AKI).
GFR_Criteria_Class	Classification based on creatinine/GFR criteria alone.
Urine_Output_Criteria_Class	Classification based on urine output criteria alone.

References

Bellomo R, Ronco C, Kellum JA, et al. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8(4):R204-212. doi:10.1186/cc2872

Examples

# Example 1: Injury Class (High Creatinine)
# Baseline Cr 1.0, Current Cr 2.5 (>2x increase)
rifle_criteria_aki(1.0, 2.5, 0, 1.0, 0, 0)

# Example 2: Failure Class (Low Urine Output)
# Cr normal, UO < 0.3 ml/kg/h for 24 hours
rifle_criteria_aki(1.0, 1.1, 0, 0.2, 24, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.