rome_iv_functional_biliary_sod: Rome IV Diagnostic Criteria for Functional Biliary Sphincter...

In cliot: Clinical Indices and Outcomes Tools

Rome IV Diagnostic Criteria for Functional Biliary Sphincter of Oddi Disorder (SOD)

Description

Evaluates the Rome IV diagnostic criteria for Functional Biliary Sphincter of Oddi Disorder (SOD), which is characterized by recurrent episodes of biliary pain in the absence of structural or metabolic explanations. The diagnosis is based on a set of general criteria, with manometry used for subtype classification.

Usage

rome_iv_functional_biliary_sod(episode_pain, other_pain_excluded,
                               normal_liver_enzymes, normal_pancreatic_enzymes,
                               normal_imaging, not_explained_by_other_condition,
                               manometry_normal_or_high)

Arguments

episode_pain	Numeric (0 or 1). Presence of recurrent episodes of biliary pain (pain in the epigastrium and/or right upper quadrant, meeting specific characteristics). (1 = Yes).
other_pain_excluded	Numeric (0 or 1). Have other causes of abdominal pain been excluded? (1 = Yes).
normal_liver_enzymes	Numeric (0 or 1). Is there documentation of normal liver enzymes (ALT/AST, ALP) and bilirubin? (1 = Yes).
normal_pancreatic_enzymes	Numeric (0 or 1). Is there documentation of normal pancreatic enzymes (amylase/lipase)? (1 = Yes).
normal_imaging	Numeric (0 or 1). Is there documentation of normal transabdominal ultrasound or Endoscopic Ultrasound (EUS) with no structural abnormalities? (1 = Yes).
not_explained_by_other_condition	Numeric (0 or 1). Are symptoms NOT fully explained by another medical condition (e.g., celiac disease, peptic ulcer)? (1 = Yes).
manometry_normal_or_high	Numeric (0 or 1). Does Sphincter of Oddi manometry show elevated basal pressure or a normal pressure (used for subtyping)? (1 = Yes, pressure is high or normal).

Value

A list containing:

Diagnosis

The diagnostic result, including subtype based on presumed manometry results (Type I/II if positive manometry, Type III if negative/manometry not done).

References

Corazziari E, Shaffer EA, Hogan WJ, et al. Functional Disorders of the Gallbladder and Sphincter of Oddi. Gastroenterology. 2016;150:1443-1455. doi:10.1053/j.gastro.2016.02.044

Examples

# Example 1: Type I/II SOD (General criteria met + positive manometry)
rome_iv_functional_biliary_sod(1, 1, 1, 1, 1, 1, 1)

# Example 2: Type III SOD (General criteria met + negative/unknown manometry)
rome_iv_functional_biliary_sod(1, 1, 1, 1, 1, 1, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.