rome_iv_functional_gallbladder_disorder: Rome IV Diagnostic Criteria for Functional Gallbladder...

In cliot: Clinical Indices and Outcomes Tools

Rome IV Diagnostic Criteria for Functional Gallbladder Disorder

Description

Evaluates the Rome IV diagnostic criteria for Functional Gallbladder Disorder (FGD), a functional biliary disorder characterized by pain of presumed biliary origin in the absence of gallstones or structural abnormality, and objective evidence of impaired gallbladder motility.

Usage

rome_iv_functional_gallbladder_disorder(biliary_pain, normal_liver_enzymes,
                                        normal_pancreatic_enzymes, normal_imaging,
                                        low_ejection_fraction,
                                        not_explained_by_other_condition,
                                        symptom_onset_ge_6_months,
                                        symptoms_active_last_3_months)

Arguments

biliary_pain	Numeric (0 or 1). Presence of recurrent episodes of biliary pain (pain in the epigastrium and/or right upper quadrant). (1 = Yes).
normal_liver_enzymes	Numeric (0 or 1). Is there documentation of normal liver enzymes (ALT/AST, ALP) and conjugated bilirubin? (1 = Yes).
normal_pancreatic_enzymes	Numeric (0 or 1). Is there documentation of normal pancreatic enzymes (amylase/lipase)? (1 = Yes).
normal_imaging	Numeric (0 or 1). Is there documentation of no gallstones or other structural pathology on transabdominal ultrasound? (1 = Yes).
low_ejection_fraction	Numeric (0 or 1). Is the gallbladder ejection fraction low (<38% or site-specific abnormal cutoff) on cholecystokinin-stimulated scintigraphy (HIDA scan)? (1 = Yes).
not_explained_by_other_condition	Numeric (0 or 1). Are symptoms NOT fully explained by another medical condition (e.g., peptic ulcer disease, GERD, coronary artery disease)? (1 = Yes).
symptom_onset_ge_6_months	Numeric (0 or 1). Did symptom onset occur at least 6 months prior to diagnosis? (1 = Yes).
symptoms_active_last_3_months	Numeric (0 or 1). Have symptoms been active for the last 3 months? (1 = Yes).

Value

A list containing:

Diagnosis

"Criteria Met for Functional Gallbladder Disorder" or "Criteria Not Met".

References

Corazziari E, Shaffer EA, Hogan WJ, et al. Functional Disorders of the Gallbladder and Sphincter of Oddi. Gastroenterology. 2016;150:1443-1455. doi:10.1053/j.gastro.2016.02.044

Examples

# Example 1: Diagnosis Met
# All organic causes excluded, typical pain, and low EF documented
rome_iv_functional_gallbladder_disorder(1, 1, 1, 1, 1, 1, 1, 1)

# Example 2: Not Met (EF normal)
# All structural/lab criteria met, but EF is normal (0)
rome_iv_functional_gallbladder_disorder(1, 1, 1, 1, 0, 1, 1, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.