rome_iv_functional_heartburn: Rome IV Diagnostic Criteria for Functional Heartburn

In cliot: Clinical Indices and Outcomes Tools

Rome IV Diagnostic Criteria for Functional Heartburn

Description

Evaluates the **Rome IV criteria** for diagnosing **Functional Heartburn**. This is a functional esophageal disorder defined by retrosternal burning pain in the absence of structural, motor, or reflux disease that explains the symptoms. The defining features are refractory symptoms and the lack of a causal link to acid reflux.

Usage

rome_iv_functional_heartburn(burning_retrosternal_pain, no_symptom_relief_ppi,
                             no_erosive_esophagitis, no_gerd_explanation,
                             no_major_motility_disorder, symptom_onset_ge_6_months,
                             symptoms_active_last_3_months)

Arguments

burning_retrosternal_pain	Numeric (0 or 1). Presence of burning retrosternal pain or discomfort. (1 = Yes).
no_symptom_relief_ppi	Numeric (0 or 1). Symptoms are **refractory** to optimal antisecretory therapy (e.g., PPIs). (1 = Yes).
no_erosive_esophagitis	Numeric (0 or 1). Absence of erosive esophagitis on Esophagogastroduodenoscopy (EGD). (1 = Yes).
no_gerd_explanation	Numeric (0 or 1). Absence of evidence that gastroesophageal reflux (GERD) is the cause of the symptom (e.g., negative symptom association probability/index and normal acid exposure time on reflux monitoring). (1 = Yes).
no_major_motility_disorder	Numeric (0 or 1). Absence of major esophageal motor disorders (e.g., achalasia) on high-resolution manometry. (1 = Yes).
symptom_onset_ge_6_months	Numeric (0 or 1). Did symptom onset occur at least **6 months ago**? (1 = Yes).
symptoms_active_last_3_months	Numeric (0 or 1). Have symptoms been active for the last **3 months**? (1 = Yes).

Value

A list containing:

Diagnosis

"Criteria Met for Functional Heartburn" or "Criteria Not Met".

References

Aben-Fawaz H, Kahrilas PJ, Chen J. Esophageal disorders. Gastroenterology. 2016;150:1367-1379. doi:10.1053/j.gastro.2016.02.002

Examples

# Example 1: Diagnosis Met
# Burning pain (1), PPI failure (1), No esophagitis (1),
#Normal reflux study (1), No motility issue (1), Chronic
rome_iv_functional_heartburn(1, 1, 1, 1, 1, 1, 1)

# Example 2: Not Met (Pathological Reflux Present)
# Reflux study shows pathological acid exposure time (0 for no_gerd_explanation)
rome_iv_functional_heartburn(1, 1, 1, 0, 1, 1, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.