rome_iv_functional_pancreatic_sod: Rome IV Diagnostic Criteria for Functional Pancreatic...

In cliot: Clinical Indices and Outcomes Tools

Rome IV Diagnostic Criteria for Functional Pancreatic Sphincter of Oddi Disorder (SOD)

Description

Evaluates the Rome IV diagnostic criteria for Functional Pancreatic Sphincter of Oddi Disorder. Diagnosis requires recurrent, episodic pain of presumed pancreatic origin, absence of other pathology (structural, metabolic, imaging), and elevated sphincter of Oddi basal pressure documented by manometry. This disorder is characterized by presumed intermittent obstruction to pancreatic fluid outflow.

Usage

rome_iv_functional_pancreatic_sod(biliary_pain,
normal_enzymes, normal_imaging,
manometry_high, not_explained_by_other_condition,
symptom_onset_ge_6_months, symptoms_active_last_3_months)

Arguments

biliary_pain	Numeric (0 or 1). Presence of recurrent, episodic pain of presumed pancreatic origin (consistent with recurrent pancreatitis). (1 = Yes).
normal_enzymes	Numeric (0 or 1). Documentation of normal pancreatic enzymes (amylase/lipase) *between* pain episodes. (1 = Yes).
normal_imaging	Numeric (0 or 1). Documentation of no pancreatic structural pathology (e.g., mass, chronic pancreatitis changes) on imaging (e.g., EUS, CT, or MRCP). (1 = Yes).
manometry_high	Numeric (0 or 1). Elevated sphincter of Oddi basal pressure documented by manometry (a pressure >= 40 mmHg is diagnostic). (1 = Yes).
not_explained_by_other_condition	Numeric (0 or 1). Are symptoms NOT fully explained by another medical condition? (1 = Yes).
symptom_onset_ge_6_months	Numeric (0 or 1). Did symptom onset occur at least 6 months prior to diagnosis? (1 = Yes).
symptoms_active_last_3_months	Numeric (0 or 1). Have symptoms been active for the last 3 months? (1 = Yes).

Value

A list containing:

Diagnosis

"Criteria Met for Functional Pancreatic Sphincter of Oddi Disorder (SOD)" or "Criteria Not Met".

References

Corazziari E, Shaffer EA, Hogan WJ, et al. Functional Disorders of the Gallbladder and Sphincter of Oddi. Gastroenterology. 2016;150:1443-1455. doi:10.1053/j.gastro.2016.02.044

Examples

# Example 1: Diagnosis Met
# All exclusion criteria and symptom characteristics are met and manometry is positive
rome_iv_functional_pancreatic_sod(1, 1, 1, 1, 1, 1, 1)

# Example 2: Not Met (Manometry Negative/Normal)
# All clinical/imaging criteria met, but manometry is normal (0)
rome_iv_functional_pancreatic_sod(1, 1, 1, 0, 1, 1, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.