salivary_gland_cancer_port_survival: Salivary Gland Cancer Model for Survival +/- Postoperative...

In cliot: Clinical Indices and Outcomes Tools

Salivary Gland Cancer Model for Survival +/- Postoperative Radiotherapy (PORT)

Description

Provides a structure to calculate overall survival probability for patients with resected major salivary gland cancer, with or without postoperative radiotherapy (PORT). This model is based on the study by Jacobs et al. using the National Cancer Database (NCDB). It helps in decision-making regarding the benefit of PORT by stratifying survival based on clinical and pathological factors.

Usage

salivary_gland_cancer_port_survival(age_at_diagnosis, sex, charlson_deyo_score,
                                    pathologic_t_stage, ratio_nodal_positivity,
                                    grade, surgical_margin, primary_site,
                                    port_received)

Arguments

age_at_diagnosis	Numeric. Patient age in years.
sex	String. "Male" or "Female".
charlson_deyo_score	Numeric. Charlson-Deyo comorbidity score (0, 1, 2, or >=3).
pathologic_t_stage	Numeric. AJCC Pathologic T Stage (1, 2, 3, or 4).
ratio_nodal_positivity	String. Ratio of positive lymph nodes to total nodes examined. Options: "0", "0.1-10", "10.1-49.9", ">=50".
grade	String. Tumor grade. Options: "low", "intermediate", "high".
surgical_margin	String. Status of surgical margins. Options: "negative", "positive".
primary_site	String. Primary tumor site. Options: "parotid", "submandibular", "sublingual".
port_received	String. Did the patient receive Postoperative Radiotherapy? "no", "yes".

Value

A list containing:

Note	Information regarding the calculation logic.
Inputs	The validated inputs provided for the model.

References

Jacobs CD, et al. Nomogram to Predict Survival Benefit of Postoperative Radiotherapy for Major Salivary Gland Cancers. Head Neck. 2020.

Examples

# Example: 65yo Male with T3N1 Parotid Cancer, Positive Margins
salivary_gland_cancer_port_survival(65, "male", 0, 3, "0.1-10", "high", "positive", "parotid", "no")

cliot documentation built on Dec. 1, 2025, 1:06 a.m.