seattle_heart_failure_model: Seattle Heart Failure Model (SHFM)

In cliot: Clinical Indices and Outcomes Tools

Seattle Heart Failure Model (SHFM)

Description

Calculates the Seattle Heart Failure Model (SHFM) risk score to predict 1-, 2-, and 5-year survival and median life expectancy in patients with heart failure. The model integrates clinical status, pharmacological and device therapy, and laboratory parameters.

Usage

seattle_heart_failure_model(age, sex, nyha_class, ejection_fraction, systolic_bp,
                            ischemic_etiology, weight_kg,
                            diuretic_daily_furosemide_equiv_mg,
                            hemoglobin_g_dl, lymphocyte_percent, uric_acid_mg_dl,
                            sodium_meq_l, cholesterol_mg_dl, qrs_duration_ms,
                            ace_inhibitor, beta_blocker, statin, allopurinol,
                            aldosterone_blocker, icd_device, crt_device)

Arguments

age	Numeric. Patient age in years.
sex	String. "Male" or "Female".
nyha_class	Numeric. NYHA Functional Class (1-4).
ejection_fraction	Numeric. Left Ventricular Ejection Fraction (LVEF) in percent.
systolic_bp	Numeric. Systolic Blood Pressure in mmHg.
ischemic_etiology	Numeric (0 or 1). Ischemic etiology of heart failure (1 = Yes).
weight_kg	Numeric. Patient weight in kilograms.
diuretic_daily_furosemide_equiv_mg	Numeric. Total daily diuretic dose in furosemide equivalents (mg).
hemoglobin_g_dl	Numeric. Hemoglobin level in g/dL.
lymphocyte_percent	Numeric. Lymphocyte percentage of total WBC.
uric_acid_mg_dl	Numeric. Serum Uric Acid level in mg/dL.
sodium_meq_l	Numeric. Serum Sodium level in mEq/L.
cholesterol_mg_dl	Numeric. Total Cholesterol in mg/dL.
qrs_duration_ms	Numeric. QRS duration in ms (used for CRT benefit assessment).
ace_inhibitor	Numeric (0 or 1). Use of ACE Inhibitor or ARB. (1 = Yes).
beta_blocker	Numeric (0 or 1). Use of Beta-Blocker. (1 = Yes).
statin	Numeric (0 or 1). Use of Statin. (1 = Yes).
allopurinol	Numeric (0 or 1). Use of Allopurinol. (1 = Yes).
aldosterone_blocker	Numeric (0 or 1). Use of Aldosterone Blocker (e.g., Spironolactone). (1 = Yes).
icd_device	Numeric (0 or 1). Presence of Implantable Cardioverter Defibrillator (ICD). (1 = Yes).
crt_device	Numeric (0 or 1). Presence of Cardiac Resynchronization Therapy (CRT). (1 = Yes).

Value

A list containing:

SHFM_Score	The calculated log-hazard score.
Est_1_Year_Survival	Estimated survival probability at 1 year.
Est_2_Year_Survival	Estimated survival probability at 2 years.
Est_5_Year_Survival	Estimated survival probability at 5 years.
Est_Median_Survival	Estimated median life expectancy in years.

References

Levy WC, Mozaffarian D, Linker DT, et al. The Seattle Heart Failure Model: prediction of survival in heart failure. Circulation. 2006;113(11):1424-1433. doi:10.1161/CIRCULATIONAHA.105.584102

Examples

# Example: High Risk Patient
seattle_heart_failure_model(
  age = 75, sex = "male", nyha_class = 3, ejection_fraction = 25,
  systolic_bp = 110, ischemic_etiology = 1, weight_kg = 80,
  diuretic_daily_furosemide_equiv_mg = 80, hemoglobin_g_dl = 11,
  lymphocyte_percent = 15, uric_acid_mg_dl = 8.0, sodium_meq_l = 135,
  cholesterol_mg_dl = 180, qrs_duration_ms = 120,
  ace_inhibitor = 1, beta_blocker = 0, statin = 0, allopurinol = 0,
  aldosterone_blocker = 0, icd_device = 0, crt_device = 0
)

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