sedan_score_hemorrhage: SEDAN Score for Post-tPA Hemorrhage Risk

In cliot: Clinical Indices and Outcomes Tools

SEDAN Score for Post-tPA Hemorrhage Risk

Description

Calculates the SEDAN score to estimate the risk of symptomatic intracranial hemorrhage (sICH) in patients with acute ischemic stroke treated with intravenous tissue plasminogen activator (tPA). The score is derived from: Sugar (glucose), Early infarct signs, Dense cerebral artery sign, Age, and NIHSS.

Usage

sedan_score_hemorrhage(glucose, early_infarct_signs, hyperdense_artery_sign,
                       age, nihss_score, glucose_units = "mmol/L")

Arguments

glucose	Numeric. Baseline blood glucose level.
early_infarct_signs	Numeric (0 or 1). Presence of early infarct signs on initial CT scan. (1 = Yes, +1 point).
hyperdense_artery_sign	Numeric (0 or 1). Presence of hyperdense cerebral artery sign on initial CT scan. (1 = Yes, +1 point).
age	Numeric. Patient age in years. (> 75 years adds 1 point).
nihss_score	Numeric. Baseline NIH Stroke Scale score. (>= 10 adds 1 point).
glucose_units	String. Units for glucose input. Options: "mmol/L" (default) or "mg/dL". Scoring: <= 8.0 mmol/L (144 mg/dL): 0 pts 8.1 - 12.0 mmol/L (145-216 mg/dL): 1 pt > 12.0 mmol/L (216 mg/dL): 2 pts

Value

A list containing:

SEDAN_Score	The calculated total score (Range 0-6).
Risk_sICH	The estimated percentage risk of symptomatic intracranial hemorrhage.
Risk_Category	General risk classification.

References

Strbian D, Engelter S, Michel P, et al. Symptomatic intracranial hemorrhage after stroke thrombolysis: the SEDAN score. Ann Neurol. 2012;71(5):634-641. doi:10.1002/ana.23546

Examples

# Example 1: High Risk
# Glucose 250 mg/dL (>12 mmol/L -> 2 pts), Age 80 (+1), NIHSS 15 (+1)
# Score = 4
sedan_score_hemorrhage(250, 0, 0, 80, 15, "mg/dL")

# Example 2: Low Risk
# Glucose 5.5 mmol/L, Age 60, NIHSS 5, No CT signs
# Score = 0
sedan_score_hemorrhage(5.5, 0, 0, 60, 5)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.