sodium_deficit_hyponatremia: Sodium Deficit Calculator for Hyponatremia

In cliot: Clinical Indices and Outcomes Tools

Sodium Deficit Calculator for Hyponatremia

Description

Calculates the total sodium deficit in milliequivalents (mEq) required to raise the serum sodium concentration to a specified target level. The calculation estimates Total Body Water (TBW) based on the patient's sex, age category (adult, elderly, child), and weight.

Usage

sodium_deficit_hyponatremia(current_sodium, target_sodium, weight_kg, sex,
                            patient_type = "adult")

Arguments

current_sodium	Numeric. Current serum sodium level (mEq/L).
target_sodium	Numeric. Desired target serum sodium level (mEq/L). Note: Correction should generally not exceed 8-12 mEq/L in 24 hours to avoid osmotic demyelination syndrome.
weight_kg	Numeric. Patient weight in kilograms.
sex	String. Patient sex ("Male" or "Female").
patient_type	String. Patient age category to determine TBW fraction. "adult": Male 0.6, Female 0.5. "elderly": Male 0.5, Female 0.45. "child": 0.6 (Both sexes).

Details

The formula used is:

Sodium Deficit (mEq) = TBW \times (Target Na - Current Na)

Where TBW is estimated as a fraction of body weight based on the selected category.

Value

A list containing:

Sodium_Deficit_mEq	The estimated amount of sodium required to reach the target level.
Total_Body_Water_L	The estimated Total Body Water.

References

Adrogué HJ, Madias NE. Hyponatremia. N Engl J Med. 2000;342(21):1581-1589. doi:10.1056/NEJM200005253422107

Examples

# Example 1: Adult Male, Na 120 to 125
# TBW = 0.6 * 70 = 42 L
# Deficit = 42 * (125 - 120) = 210 mEq
sodium_deficit_hyponatremia(120, 125, 70, "male", "adult")

# Example 2: Elderly Female, Na 115 to 120
# TBW = 0.45 * 60 = 27 L
# Deficit = 27 * (120 - 115) = 135 mEq
sodium_deficit_hyponatremia(115, 120, 60, "female", "elderly")

cliot documentation built on Dec. 1, 2025, 1:06 a.m.