sokal_cml_index: Sokal Index for Chronic Myelogenous Leukemia (CML)

In cliot: Clinical Indices and Outcomes Tools

Sokal Index for Chronic Myelogenous Leukemia (CML)

Description

Calculates the Sokal Index to prognosticate risk in patients with Chronic Myelogenous Leukemia (CML). The score is based on age, spleen size, platelet count, and percentage of blasts in the peripheral blood. It stratifies patients into Low, Intermediate, or High risk groups regarding survival.

Usage

sokal_cml_index(age, spleen_size_cm, platelet_count, blasts_percent)

Arguments

age	Numeric. Patient age in years.
spleen_size_cm	Numeric. Spleen size in centimeters below the costal margin (0 if not palpable).
platelet_count	Numeric. Platelet count in x10^9/L (e.g., 300 for 300,000/uL).
blasts_percent	Numeric. Percentage of blasts in peripheral blood.

Value

A list containing:

Sokal_Score	The calculated relative risk score.
Risk_Group	Risk classification (Low < 0.8, Intermediate 0.8-1.2, High > 1.2).

References

Sokal JE, Cox EB, Baccarani M, et al. Prognostic discrimination in "good-risk" chronic granulocytic leukemia. Blood. 1984;63(4):789-799.

Examples

# Example 1: Low Risk
# 35yo, Spleen 0cm, Plt 300, Blasts 1%
# Score approx 0.6
sokal_cml_index(35, 0, 300, 1)

# Example 2: High Risk
# 60yo, Spleen 10cm, Plt 700, Blasts 5%
# Score > 1.2
sokal_cml_index(60, 10, 700, 5)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.