uiss_rcc_staging: UCLA Integrated Staging System (UISS) for Renal Cell...

In cliot: Clinical Indices and Outcomes Tools

UCLA Integrated Staging System (UISS) for Renal Cell Carcinoma

Description

Calculates the UISS risk stratification for patients with Renal Cell Carcinoma (RCC). The system divides patients into Localized or Metastatic disease categories and then stratifies them into Low, Intermediate, or High risk groups based on TNM stage, Fuhrman nuclear grade, and ECOG performance status to predict 5-year survival.

Usage

uiss_rcc_staging(tnm_t_stage, tnm_n_stage, tnm_m_stage, fuhrman_grade,
                 ecog_performance_status)

Arguments

tnm_t_stage	String. The TNM T-stage of the tumor (1997 classification). Options: "t1", "t2", "t3", "t4".
tnm_n_stage	String. The TNM N-stage. Options: "n0" (No lymph nodes), "n1", "n2" (Positive lymph nodes).
tnm_m_stage	String. The TNM M-stage. Options: "m0" (No distant metastasis), "m1" (Distant metastasis).
fuhrman_grade	Numeric. Fuhrman nuclear grade (1, 2, 3, or 4).
ecog_performance_status	Numeric. ECOG Performance Status score (0-4).

Value

A list containing:

UISS_Risk_Group	The calculated risk group (Low, Intermediate, or High) appended with the disease state (Localized vs Metastatic).
Est_5_Year_Survival	Estimated 5-year cancer-specific survival based on the risk group.

References

Zisman A, Pantuck AJ, Wieder J, et al. Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma. J Clin Oncol. 2002;20(23):4559-4566. doi:10.1200/JCO.2002.05.111

Examples

uiss_rcc_staging("t1", "n0", "m0", 1, 0)

uiss_rcc_staging("t3", "n1", "m0", 3, 1)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.