deconstructSigs: Identifies Signatures Present in a Tumor Sample

Takes sample information in the form of the fraction of mutations in each of 96 trinucleotide contexts and identifies the weighted combination of published signatures that, when summed, most closely reconstructs the mutational profile.

Getting started

Package details

AuthorRachel Rosenthal
MaintainerRachel Rosenthal <rachel.rosenthal.14@ucl.ac.uk>
LicenseGPL (>= 2)
Version1.8.0
URL https://github.com/raerose01/deconstructSigs
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("deconstructSigs")

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deconstructSigs documentation built on May 2, 2019, 4:06 a.m.