deconstructSigs: Identifies Signatures Present in a Tumor Sample

Takes sample information in the form of the fraction of mutations in each of 96 trinucleotide contexts and identifies the weighted combination of published signatures that, when summed, most closely reconstructs the mutational profile.

Install the latest version of this package by entering the following in R:
AuthorRachel Rosenthal
Date of publication2016-07-29 18:27:06
MaintainerRachel Rosenthal <>
LicenseGPL (>= 2)

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changeColumnNames Man page
deconstructSigs Man page
deconstructSigs-package Man page
example.output Man page
findSeed Man page
formatContexts Man page
getError Man page
getTriContextFraction Man page Man page
makePie Man page Man page Man page
plotSignatures Man page
plotTumor Man page
randomly.generated.tumors Man page
sample.mut.ref Man page
signatures.cosmic Man page
signatures.nature2013 Man page
tri.counts.exome Man page
tri.counts.genome Man page
updateW_GR Man page Man page
whichSignatures Man page

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