An efficient multi-core package to reconstruct an underlying network of genomic signatures of high-dimensional epistatic selection from partially observed genotype data. The phenotype that we consider is viability. The network captures the conditional dependent short- and long-range linkage disequilibrium structure of genomes and thus reveals aberrant marker-marker associations that are due to epistatic selection. We target on high-dimensional genotype data where number of variables (markers) is larger than number of sample sizes (p >> n). The computations is memory-optimized using the sparse matrix output.
Package details |
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Author | Pariya Behrouzi, Danny Arends and Ernst C. Wit |
Maintainer | Pariya Behrouzi <pariya.behrouzi@gmail.com> |
License | GPL-3 |
Version | 0.0.1-1 |
Package repository | View on CRAN |
Installation |
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