Adaptive Enrichment Designs with Sample Size Re-Estimation

AED1_SSR.boundary | Calculate the critical value used at the final analysis of... |

AED1_SSR.CP | Calculate the conditional power of the Adaptive Enrichment... |

AED1_SSR.N2 | Calculate the sample size required at the second stage of the... |

AED1_SSR.sim | Conduct the simulation studies of the Adaptive Enrichment... |

AED2_SSR.boundary | Calculate the futility and efficacy stopping boundaries of... |

AED2_SSR.CP | Calculate the N2 and the critical value C in the Adaptive... |

AED2_SSR.sim | Conduct the simulation studies of the Adaptive Enrichment... |

AED3_SSR.boundary | Calculate the futility and efficacy stopping boundaries in... |

AED3_SSR.CP | Calculate the N2 and the critical value C in the Adaptive... |

AED3_SSR.sim | Conduct the simulation studies of the Adaptive Enrichment... |

AED.boundary | Calculate the critical value used at the final analysis in... |

AED.sim | Conduct the simulation studies of the Adaptive Enrichment... |

MaST.sim | Conduct the simulation studies of the Marker Sequential Test... |

SD.sim | Conduct the simulation studies of the standard design |

SigP | Commonly used alpha-spending functions |

sSize.norm | Sample size calculation for the standard design with... |

SSR.boundary | Calculate the futility and efficacy stopping boundaries for... |

SSR.CP | Calculate the N2 and the critical value C in Sample Size... |

SSR.sim | Conduct the simulation studies using SSR |

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