AED1_SSR.N2: Calculate the sample size required at the second stage of the...

Description Usage Arguments Value References Examples

View source: R/esDesign.R

Description

The AED1_SSR.N2() is used to calculated the sample size required at the second stage of the Adaptive Enrichment Design (Strategy 1) with Sample Size Re-estimation Procedure.

Usage

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AED1_SSR.N2(c, z1, N1, beta)

Arguments

c

The critical value used at the final analysis

z1

The test statistic obtained at the interim analysis

N1

The sample size used at the first stage

beta

The (1 - power)

Value

The Value of the re-estimated sample size

References

Examples

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c <- 2.258
z1 <- 1.974
N1 <- 248
beta <- 0.2
AED1_SSR.N2(c = c, z1 = z1, N1 = N1, beta = beta)

esDesign documentation built on May 2, 2019, 10:41 a.m.