Description Usage Arguments Value References Examples
The AED1_SSR.N2()
is used to calculated the sample size
required at the second stage of the Adaptive Enrichment Design (Strategy 1)
with Sample Size Re-estimation Procedure.
1 | AED1_SSR.N2(c, z1, N1, beta)
|
c |
The critical value used at the final analysis |
z1 |
The test statistic obtained at the interim analysis |
N1 |
The sample size used at the first stage |
beta |
The (1 - power) |
The Value of the re-estimated sample size
Lin, R., Yang, Z., Yuan, Y. and Yin, G., 2021. Sample size re-estimation in adaptive enrichment design. Contemporary Clinical Trials, 100, p.106216. <doi: 10.1016/j.cct.2020.106216>
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