Description Usage Arguments Value References Examples
The AED1_SSR.CP()
is used to calculate the conditional
power of the Adaptive Enrichment Design (Strategy 1) with sample size
re-estimation procedure
1 | AED1_SSR.CP(c, Z1, N1, N2)
|
c |
The critical value used at the final analysis |
Z1 |
The test statistic obtained at the interim analysis |
N1 |
The sample size used at the first stage |
N2 |
The sample size used at the second stage |
A list contains
Critical.Value The critical value used at the final analysis
Conditional.Power The value of conditional power given the observed data
Lin, R., Yang, Z., Yuan, Y. and Yin, G., 2021. Sample size re-estimation in adaptive enrichment design. Contemporary Clinical Trials, 100, p.106216. <doi: 10.1016/j.cct.2020.106216>
1 2 3 4 5 | c <- 2.258
Z1 <- 1.975
N1 <- 248
N2 <- 200
AED1_SSR.CP(c = 2.258, Z1 = 1.974, N1 = 248, N2 = 200)
|
$Critical.Value
[1] 2.258
$Conditional.Power
[1] 0.7228714
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