FORCE: FORCE panel kinship SNPs

In forrel: Forensic Pedigree Analysis and Relatedness Inference

FORCE panel kinship SNPs

Description

A data frame describing (a subset of) the FORCE panel of SNPs designed for applications in forensic genetics (Tillmar et al., 2021). The subset included here are the SNPs recommended for kinship analysis. As the original publication did not include allele frequencies, these were downloaded from Ensembl via the biomaRt package. 15 markers were removed as frequency information could not be retrieved.

Usage

FORCE

Format

A data frame with 3915 rows and 6 columns:

• CHROM: Chromosome (1-22)

• MARKER: Marker name (rs number)

• MB: Physical position in megabases (build GRCh38)

• A1: First allele

• A2: Second allele

• FREQ1: Allele frequency of A1

Details

To attach the FORCE markers to a pedigree, use pedtools::setSNPs() (see Examples).

Source

Tillmar et al. The FORCE Panel: An All-in-One SNP Marker Set for Confirming Investigative Genetic Genealogy Leads and for General Forensic Applications. Genes. (2021)

Examples

x = setSNPs(nuclearPed(), snpData = FORCE)
summary(x)

getMap(x, markers = 1:5)
getFreqDatabase(x, markers = 1:5)

forrel documentation built on Sept. 11, 2024, 9:15 p.m.