ALL.classes: Acute Lymphoblastic Leukemia data (Yeoh et. al., 2002) for...

Description Usage Format Details References Examples

Description

Acute Lymphoblastic Leukemia for GALGO package data published by Yeoh et. al. The original 360 pediatric acute leukemia samples were filtered by class. 233 samples are included corresponding to 5 classes EMLLA, HYP+50, MLL, T, and TEL. The Affymetrix microarray HG_U95Av2 containing 12,600 probesets were filteres by range and standard deviation resulting in 2,435 probesets (genes).

Usage

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Format

5 Classes : Lukemia Types: "EMLLA"=E2A-PBX1, "T"=T-ALL, "HYP+50"=Hyperdiploid > 50 Chromosomes, "MLL"=MLL rearragment, and "TEL"=TEL-AML1

Details

ALL.classes is complementary for ALL data which contain the expression values for the genes in all samples.

References

Eng-Juh Yeoh, Mary E. Ross, Sheila A. Shurtleff, W. Kent Williams, Divyen Patel, Rami Mahfouz, Fred G. Behm, Susana C. Raimondi, Mary V. Relling, Anami Patel, Cheng Cheng, Dario Campana,, Dawn Wilkins, Xiaodong Zhou, Jinyan Li, Huiqing Liu, Ching-Hon Pui, William E. Evans, Clayton Naeve, Limsoon Wong, and James R. Downing. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell. March 2002.

Examples

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galgo documentation built on May 2, 2019, 4:20 a.m.